Evidence map›Paper›PMID 41606527›Full record

ArticleBMC medical imaging2026

Predictive value of node-RADS scoring system for axillary lymph node metastasis in breast cancer.

Hazal Selvi Çubuk, Murathan Erkent, Burak Yağdıran, Sedat Yıldırım

Abstract read
In one paragraph

Article in BMC medical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hazal Selvi ÇubukDepartment of Radiology, Faculty of Medicine, Baskent University, Yukarı Bahcelievler, Mareşal Fevzi Cakmak Street. No:45, Ankara, Cankaya, 06490, Türkiye. hazal_selvi@hotmail.com.
Murathan ErkentDepartment of General Surgery, Faculty of Medicine, Baskent University, Yukarı Bahcelievler, No:45, Ankara, Cankaya, 06490, Türkiye.
Burak YağdıranDepartment of Radiology, Faculty of Medicine, Baskent University, Yukarı Bahcelievler, Mareşal Fevzi Cakmak Street. No:45, Ankara, Cankaya, 06490, Türkiye.
Sedat YıldırımDepartment of General Surgery, Faculty of Medicine, Baskent University, Yukarı Bahcelievler, No:45, Ankara, Cankaya, 06490, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to evaluate the predictive value of preoperative Node-RADS determination at imaging for axillary lymph node (ALN) involvement in cases of breast cancer. MATERIALS AND

methodsNode-RADS was determined in all cases using preoperative breast magnetic resonance imaging (MRI) by two radiologists blinded to pathologic results. The ROC curves and AUCs depicted the overall diagnostic performance of the Node-RADS score for lymph node involvement. In addition, the presence of a flare-like perinodal signal was also evaluated as an imaging feature suggestive of extranodal extension. Size and morphological parameters were assessed separately for their association with metastatic involvement.

resultsBoth readers demonstrated high diagnostic accuracy in predicting ALN metastasis using the Node-RADS system, with the best diagnostic performance observed at a cutoff value above Node-RADS 2. In logistic regression analysis, heterogeneous internal texture of the lymph node and flare sign were also found to be statistically significantly associated with invasion (p < 0.05). The presence of a fatty hilum was a statistically significant predictor (p < 0.001) associated with a markedly lower likelihood of lymph node metastasis (OR = 0.019, 95% CI = 0.002-0.153).

conclusionThe Node-RADS scoring system demonstrates high diagnostic reliability and reproducibility in the evaluation of axillary lymph nodes in breast cancer. However, the size criterion for ALN assessment may need to be re-evaluated, and the inclusion of size or extranodal extension parameters in the scoring system should be reconsidered.

Indexed as

Breast NeoplasmsLymphatic MetastasisLymph NodesMagnetic Resonance ImagingAdultAgedAxillaFemaleHumansMiddle AgedPredictive Value of TestsReproducibility of ResultsROC CurveAxillary lymph nodeBreast cancerExtranodal extensionMagnetic resonance imagingNode-RADS

Identifiers

PMID41606527
PMCPMC12922373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.