Evidence map›Paper›PMID 41606525›Full record

ArticleBMC geriatrics2026

Sarcopenia and depression: a strong association in older adults with type 2 diabetes in Vietnam.

Anh Ngoc Trinh, Linh Vu Huyen Ha, Trung Hoa Dinh, Loc Quang Pham, Toan Thi Thanh Do, Hung Quoc Ha, Thu Thi Hoai Nguyen, Thanh Xuan Nguyen, Anh Trung Nguyen, Anh Lan Nguyen and 3 more

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Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anh Ngoc TrinhHanoi Medical University, No 1 Ton That Tung, Hanoi, 100000, Vietnam.
Linh Vu Huyen HaHanoi Medical University, No 1 Ton That Tung, Hanoi, 100000, Vietnam.
Trung Hoa DinhHanoi Medical University, No 1 Ton That Tung, Hanoi, 100000, Vietnam.
Loc Quang PhamHanoi Medical University, No 1 Ton That Tung, Hanoi, 100000, Vietnam.
Toan Thi Thanh DoHanoi Medical University, No 1 Ton That Tung, Hanoi, 100000, Vietnam.
Hung Quoc HaVinmec Times City International Hospital, Hanoi, 100000, Vietnam.
Thu Thi Hoai NguyenHanoi Medical University, No 1 Ton That Tung, Hanoi, 100000, Vietnam.
Thanh Xuan NguyenHanoi Medical University, No 1 Ton That Tung, Hanoi, 100000, Vietnam.
Anh Trung NguyenHanoi Medical University, No 1 Ton That Tung, Hanoi, 100000, Vietnam.
Anh Lan NguyenHanoi Medical University, No 1 Ton That Tung, Hanoi, 100000, Vietnam.
Huong Thi Thu NguyenHanoi Medical University, No 1 Ton That Tung, Hanoi, 100000, Vietnam.
Tam Ngoc NguyenHanoi Medical University, No 1 Ton That Tung, Hanoi, 100000, Vietnam.
Huyen Thi Thanh VuHanoi Medical University, No 1 Ton That Tung, Hanoi, 100000, Vietnam. vuthanhhuyen11@hmu.edu.vn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia and depression are both common and impactful conditions in older adults. However, there has been limited research on their relationship, particularly in older patients with type 2 diabetes (T2D).

objectivesTo investigate the association between sarcopenia and depressive symptoms among older Vietnamese adults with T2D.

methodsFrom May to December 2024, 630 patients with T2D were recruited from the outpatient clinics of the National Geriatric Hospital in Vietnam, of whom 618 were included in the cross-sectional analysis. Sarcopenia was diagnosed based on the 2019 Asian Working Group for Sarcopenia criteria (AWGS 2019). Depressive symptoms were evaluated using the validated Vietnamese version of the 15-item Geriatric Depression Scale (GDS-15), with scores of 5 or higher indicating the presence of depressive symptoms. Demographic factors, lifestyle behaviours, diabetes-related indicators (HbA1c, duration, complications), and geriatric characteristics were also analysed as potential confounders. Logistic regression was used to assess the association between sarcopenia and depressive symptoms.

resultsAmong the 618 participants (mean age 73.5 ± 7.1 years, 63.7% female), 34.5% were diagnosed with sarcopenia, and 25.9% exhibited depressive symptoms. Sarcopenia was significantly associated with depressive symptoms (AOR 1.73, 95% CI 1.09-2.72). Other significant predictors of depressive symptoms included female sex (AOR 2.32, 95% CI 1.08-4.98), older age (AOR 1.04, 95% CI 1.01-1.07), higher BMI (AOR 1.08, 95% CI 1.01-1.17), more comorbidities (AOR 1.23, 95% CI 1.07-1.42), chronic diabetic complications (AOR 1.79, 95% CI 1.12-2.85), and cognitive impairment (AOR 1.61, 95% CI 1.09-2.38).

conclusionsThis study reveals a significant association between sarcopenia and depressive symptoms in older adults with T2D, suggesting that comprehensive screening strategies may help in the early detection of coexisting physical and mental health problems in this vulnerable population.

Indexed as

DepressionDiabetes Mellitus, Type 2SarcopeniaAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleVietnamDepressive symptomsDiabetes mellitusSarcopeniaVietnam

Identifiers

PMID41606525
PMCPMC12924510

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