Evidence map›Paper›PMID 41606484›Full record

ArticleBMC plant biology2026

Genome-wide transcriptional and metabolic responses of Eschscholzia californica to salt stress.

Zhuo Huang, Linli Jian, Li Song, Xihong Deng, Bihan Yan, Yujia Fu, Meng Zhou, Yuexi Wang, Xin Tao

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Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Zhuo Huang *College of Life Science, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China. huangzhuo@sicau.edu.cn.
Linli Jian *College of Landscape Architecture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Li SongCollege of Landscape Architecture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Xihong DengCollege of Landscape Architecture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Bihan YanCollege of Landscape Architecture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Yujia FuCollege of Landscape Architecture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Meng ZhouCollege of Landscape Architecture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Yuexi WangCollege of Landscape Architecture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Xin TaoCollege of Landscape Architecture, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eschscholzia californica, as an abiotic stress-tolerant ornamental plant, has long been studied for phylogenetic analysis and biosynthesis of benzylisoquinoline alkaloids. However, little is known about its environmental adaptation mechanisms. In this study, we performed comprehensive investigations on responses of E. californica to salt stress, one of serious threats to modern agriculture. The effects of 250 mM NaCl solution treatment on plant growth and several stress response related indices were investigated at 0d, 7d, and 10d, representing non-stressed (CK), mildly-stressed (St0), and severely-stressed (St1), respectively. RNA-seq analysis revealed salt-stress responsive and differentially expressed genes (DEGs) enriched in photosynthesis-related pathways, phenylpropanoid biosynthesis, ɑ-Linolenic acid metabolism, isoquinoline alkaloid biosynthesis, benzoxazinoid biosynthesis, etc. With the aggravation of salt stress, pathways of the tryptophan metabolism, plant hormone signal transduction, ɑ-Linolenic acid metabolism, and isoquinoline alkaloid biosynthesis, etc., were more significantly enriched. We also identified DEGs involved in intracellular ion homeostasis, osmotic regulation, oxidative stress and detoxification, plant hormone biosynthesis and signaling, as well as those encoding transcription factors. Furthermore, Comparison of metabolites in CK and St1 showed that the differentially accumulated metabolites under salt stress were mainly alkaloids (23.6%), phenolic acids (16.5%), lipids (15.2%), organic acids (8.1%), amino acids and their derivatives (7.6%), flavonoids (6.5%), etc. Further joint analysis of transcriptome and metabolome data revealed key pathways in responding to salt stress. The jasmonic acid biosynthesis and signaling and isoquinoline alkaloid biosynthesis were particularly noteworthy due to their extremely significant up-regulation by salt stress and unclear or debatable roles in regulating salt stress tolerance. The DEGs in the two pathways, such as AOX, LOX, and JAZs, as well as NCS1, 6OMT, TNMT, and BBEs, etc., are therefore valuable for uncovering the functional roles of two pathways in salt stress tolerance of E. californica, and future breeding salt-tolerant crops.

Indexed as

EschscholziaSalt StressGene Expression ProfilingGene Expression Regulation, PlantGenome, PlantSalt ToleranceTranscriptomeE. californicaIsoquinoline alkaloidJasmonic acidMetabolomeSalt stressTranscriptome

Identifiers

PMID41606484
PMCPMC12924282

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