ArticleFolia microbiologica2026
Vancomycin-resistant enterococci in healthcare settings: clonal analysis, resistance profiles, and biofilm formation of strains isolated from hospitalized patients.
Article in Folia microbiologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Clinical Characteristics and Antimicrobial Resistance Profiles of Pediatric Enterococcal Infections: A Comparison BetweenPathogens (Basel, Switzerland) · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Multidrug-resistant bacteria, including vancomycin-resistant Enterococci (VRE), are a significant public health threat. This study aimed to perform molecular characterization of E. faecium and E. faecalis isolates with respect to glycopeptide and phenotypic resistance, and clonal relatedness. A total of 45 isolates (41 E. faecium, 4 E. faecalis) were obtained from clinical specimens collected at the University Hospital in Kraków, Poland. Isolates were screened on chromogenic media, identified by Matrix-Assisted Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) and tested for antimicrobial susceptibility and the presence of vanA/vanB genes. Biofilm formation was assessed on culture media, and clonal relationships were determined using PFGE. Among the isolates, 86.7% harbored vanA and 13.3% vanB genes. E. faecium remained resistant mainly to ampicillin and teicoplanin, but susceptible to tigecycline and linezolid. E. faecalis showed partial susceptibility to ampicillin, tigecycline and linezolid, but frequent resistance to teicoplanin and reduced susceptibility to imipenem. Biofilm assessment revealed that 88.9% of isolates produced high biofilm levels. PFGE analysis identified several clonal groups among Enterococcus faecium, with clone A being the most prevalent (9 strains). The predominance of clonal strains and their robust biofilm production underscore the dissemination potential of VRE in hospital settings. High levels of antibiotic resistance highlight the limited therapeutic options available. Comprehensive preventive and control measures are essential to mitigate transmission of multidrug-resistant pathogens in healthcare environments. These findings provide recent epidemiological data on VRE circulation and highlight the clinical relevance of a dominant, biofilm-forming clonal lineage in a tertiary-care setting.
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Registered trials
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