ArticleNature2026
Psychedelics elicit their effects by 5-HT
Erratum issuedAbstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Multilevel Mechanisms and Clinical Efficacy of Psilocybin in Depression Treatment: A Systematic Review.International journal of molecular sciences · 2026Pooled it
- Psychedelics and astrocytes: a hypothesis-driven perspective on neuro-glial integration, network plasticity, and neuroimmune reprogramming.Molecular psychiatry · 2026Review
- Classic Psychedelics for Treating Chronic Pain: Mechanism and Clinical Translation.Molecules (Basel, Switzerland) · 2026Review
- Integrated 5-HTMolecular psychiatry · 2026Article
- The working lives of neuronal 5-HTRSC chemical biology · 2026Review
- No evidence for direct physical interaction of 5-HTbioRxiv : the preprint server for biology · 2026Article
- Explainable Artificial Intelligence (xAI) for 5-HTMolecules (Basel, Switzerland) · 2026Article
- Wherefore the Magic? The Evolutionary Role of Psilocybin in Nature.Ecology and evolution · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
36 authors.
Zheng Xu *National Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0002-5374-4121
Hongshuang Wang *Interdisciplinary Laboratory for Frontier Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China.
Jingjing Yu *National Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0002-3907-3560
Yue Deng *National Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Xiaowen Tian *National Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Rongjun Ni *National Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0001-7421-136X
Fan Xia *Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China.
Lingyi Yang *National Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Chanjuan Xu *Key Laboratory of Molecular Biophysics of MOE, International Research Center for Sensory Biology and Technology of MOST, College of Life Science and Technology, Huazhong University of Science and Technology (HUST), Wuhan, China.ORCID 0000-0002-5640-1896
Liting Zhang *National Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0003-2782-4424
Renxuan LuoNational Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Peipei ChenNational Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Xiaoyu ZhangNational Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Yuxuan LiuKey Laboratory of Molecular Biophysics of MOE, International Research Center for Sensory Biology and Technology of MOST, College of Life Science and Technology, Huazhong University of Science and Technology (HUST), Wuhan, China.ORCID 0009-0007-0799-3227
Jingyu HouNational Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Miyuan ZhangInterdisciplinary Laboratory for Frontier Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China.
Shasha ChenNational Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Lantian SuTianfu Jincheng Laboratory, Chengdu, China.
Hui SunTianfu Jincheng Laboratory, Chengdu, China.ORCID 0009-0006-9866-9846
Yixiao HeTianfu Jincheng Laboratory, Chengdu, China.
Dandan ChenFunctional and Molecular Imaging Key Laboratory of Sichuan Province, Department of Radiology, Huaxi MR Research Centre (HMRRC), West China Hospital of Sichuan University, Chengdu, China.
Xiaoting ChenAnimal Experimental Center, West China Hospital, Sichuan University, Chengdu, China.
Zhuang MiaoDepartment of Anesthesiology, Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Jie XieCollege of Life Sciences, Sichuan Normal University, Chengdu, China.ORCID 0000-0003-2434-381X
Xinlei LiuNational Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Jie ZhaoTianfu Jincheng Laboratory, Chengdu, China.ORCID 0000-0002-6370-9549
Bowen KeDepartment of Anesthesiology, Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0002-0328-7719
Xiaohe TianFunctional and Molecular Imaging Key Laboratory of Sichuan Province, Department of Radiology, Huaxi MR Research Centre (HMRRC), West China Hospital of Sichuan University, Chengdu, China.ORCID 0000-0002-2294-3945
Linan ZengDepartment of Pharmacy, Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Lingli ZhangDepartment of Pharmacy, Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Xiangdong TangNational Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Shengyong YangNational Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China. yangsy@scu.edu.cn.ORCID 0000-0001-5147-3746
Jianfeng LiuKey Laboratory of Molecular Biophysics of MOE, International Research Center for Sensory Biology and Technology of MOST, College of Life Science and Technology, Huazhong University of Science and Technology (HUST), Wuhan, China. jfliu@mail.hust.edu.cn.ORCID 0000-0002-0284-8377
Xiaohui WangInterdisciplinary Laboratory for Frontier Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China. xiaohui.wang@ciac.ac.cn.ORCID 0000-0002-3415-5612
Wei YanNational Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China. weiyan2018@scu.edu.cn.ORCID 0000-0001-9825-0689
Zhenhua ShaoNational Center for Mental Disorders, Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China. zhenhuashao@scu.edu.cn.ORCID 0000-0001-7204-801X
Funding
China Postdoctoral Science FoundationFundamental Research Funds for the Central Universities
Abstract
Psychedelics are undergoing a renaissance as potential therapy for psychiatric disorders, with more than 200 clinical trials being studied across several countries
Indexed as
GTP-Binding Protein alpha Subunits, Gi-GoHallucinogensReceptor, Serotonin, 5-HT2ASignal TransductionAnimalsCryoelectron MicroscopyFemaleGTP-Binding Protein alpha Subunits, Gq-G11HEK293 CellsHumansMaleMiceModels, MolecularSerotonin 5-HT2 Receptor AgonistsGTP-Binding Protein alpha Subunits, Gi-GoGTP-Binding Protein alpha Subunits, Gq-G11HallucinogensReceptor, Serotonin, 5-HT2ASerotonin 5-HT2 Receptor Agonists
Identifiers
PMID
41606342What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.