Evidence map›Paper›PMID 41606324›Full record

ArticleNature2026

Robust cytoplasmic partitioning by solving a cytoskeletal instability.

Melissa Rinaldin, Alison Kickuth, Adam Lamson, Benjamin Dalton, Yitong Xu, Pavel Mejstřík, Stefano Di Talia, Jan Brugués

Erratum issuedAbstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Overcoming cytoskeleton instability in the early embryo.Nature reviews. Molecular cell biology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Melissa RinaldinCluster of Excellence Physics of Life, TU Dresden, Dresden, Germany. melissa.rinaldin@tu-dresden.de.ORCID http://orcid.org/0000-0002-8040-9468
Alison Kickuth *Cluster of Excellence Physics of Life, TU Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0002-8571-7902
Adam Lamson *Cluster of Excellence Physics of Life, TU Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0003-2616-2801
Benjamin DaltonFachbereich Physik, Freie Universität Berlin, Berlin, Germany.
Yitong XuDepartment of Cell Biology, Duke University Medical Center, Durham, NC, USA.
Pavel MejstříkMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Stefano Di TaliaDepartment of Cell Biology, Duke University Medical Center, Durham, NC, USA.ORCID http://orcid.org/0000-0001-9758-7925
Jan BruguésCluster of Excellence Physics of Life, TU Dresden, Dresden, Germany. jan.brugues@tu-dresden.de.ORCID http://orcid.org/0000-0002-6731-4130

Funding

Time-keeping mechanisms of embryonic cell cyclesR01GM122936 · NIGMS · DUKE UNIVERSITY · PI DI TALIA, STEFANO · 2017 to 2023
$2.0M
Physical principles of early Drosophila embryogenesisR35GM153490 · NIGMS · DUKE UNIVERSITY · PI Stefano Di Talia · 2024 to 2026
$1.5M
NIGMS NIH HHS R01 GM122936NIGMS NIH HHS R35 GM153490
6 · The paper itself

Abstract

Early development across vertebrates and insects critically relies on robustly reorganizing the cytoplasm of fertilized eggs into individualized cells

Indexed as

CytoplasmCytoskeletonDrosophila melanogasterMicrotubulesZebrafishAnimalsCell CycleEmbryonic DevelopmentEmbryo, Nonmammalian

Identifiers

PMID41606324
PMCPMC12979205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.