Evidence map›Paper›PMID 41606321›Full record

ArticleNature2026

Vagal blood volume receptors compensate for haemorrhage and posture change.

Zhikai Liu, Shan Lu, Isabela A Haskell, Michael S Schappe, Maša Josipović, Soohong Min, AbdulRasheed A Alabi, Jingyi Chi, Minseon Kim, Stephen D Liberles

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Zhikai Liu *Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-2185-2064
Shan Lu *Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-2457-3850
Isabela A HaskellHoward Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Michael S SchappeHoward Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-9889-2155
Maša JosipovićHoward Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Soohong MinHoward Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
AbdulRasheed A AlabiHoward Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Jingyi ChiHoward Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Minseon KimHoward Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-1193-7937
Stephen D LiberlesHoward Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA. Stephen_Liberles@hms.harvard.edu.ORCID 0000-0002-2177-9741

Funding

Sensory receptors of the vagus nerveDP1AT009497 · NCCIH · HARVARD MEDICAL SCHOOL · PI LIBERLES, STEPHEN DANIEL · 2016 to 2020
$5.9M
NCCIH NIH HHS DP1 AT009497
6 · The paper itself

Abstract

Cranial nerves densely innervate the heart and vasculature, with sensory neurons reporting on blood pressure, respiratory gases and tissue damage

Indexed as

Blood VolumeHemorrhagePostureVagus NerveAnimalsBlood PressureFemaleHeartHeart RateHypotension, OrthostaticIon ChannelsMaleMechanoreceptorsMiceNeuronsOptogeneticsIon ChannelsPiezo2 protein, mouse

Identifiers

PMID41606321
PMCPMC13017543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.