Evidence map›Paper›PMID 41606299›Full record

ArticleAnnals of surgical oncology2026

Dental Health and Survival Following Surgery for Esophageal Cancer.

Kenzo Buchli, Eivind Gottlieb-Vedi, Fredrik Mattsson, Ellinor Wiström, Björn Klinge, Pernilla Lagergren, Jesper Lagergren

Abstract read
In one paragraph

Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kenzo BuchliUpper Gastrointestinal Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden.
Eivind Gottlieb-VediUpper Gastrointestinal Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden. eivind.gottlieb@ki.se.
Fredrik MattssonUpper Gastrointestinal Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden.
Ellinor WiströmUpper Gastrointestinal Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden.
Björn KlingeFaculty of Odontology, Malmö University, Malmö, Sweden.
Pernilla LagergrenSurgical Care Science, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Jesper LagergrenUpper Gastrointestinal Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden.

Funding

Cancer Research Funds of Radiumhemmet 231243Stockholm County Council FoUI-985983Swedish Cancer Society 24 3414
6 · The paper itself

Abstract

backgroundMost patients who undergo esophagectomy for esophageal cancer develop tumor recurrence and die within 5 years of surgery. An impact of preoperative dental status on survival in this patient group has been suggested but remains uncertain.

methodsThis national Swedish cohort study included 871 patients who underwent esophagectomy for esophageal cancer (adenocarcinoma or squamous cell carcinoma) between 2011 and 2020 and were followed up until 2024. The exposure was the number of remaining teeth, based on dentist visits within 5 years before the esophagectomy, categorized into five (quintiles) and 10 (deciles) groups. The main outcome was all-cause 5-year mortality. Data were retrieved from medical records and national complete registries. Multivariable Cox regression provided hazard ratios (HRs) with 95% confidence intervals (CIs), adjusted for age, sex, comorbidity, tumor histology, neoadjuvant therapy, education level, and pathological tumor stage.

resultsThere were no statistically significant associations between the number of remaining teeth and the risk of all-cause 5-year mortality, independent of the categorization of the number of teeth. The HR was 1.13 (95% CI 0.85-1.51) comparing the lowest quintile of remaining teeth (n = 0-19) with the highest quintile (n = 29-32), and the HR was 0.98 (95% CI 0.64-1.52) comparing the lowest decile of remaining teeth (n = 0-10) with the highest decile (n = 31-32). There were no statistically significant associations in any of the subgroup analyses of age, comorbidity, or education.

conclusionThis study did not identify any association between the number of remaining teeth and the risk of 5 year mortality in patients who underwent esophagectomy for esophageal cancer.

Indexed as

AdenocarcinomaEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaEsophagectomyOral HealthAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisSurvival RateSwedenEsophageal neoplasmPrognosisSocio-economyTeeth

Identifiers

PMID41606299
PMCPMC13083414

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.