ArticleCommunications engineering2026
Photo-activated ultrasound localization imaging with laser-activated nanodroplets.
Article in Communications engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Endothelial Continuum and Capillary Specialization in Pulmonary Vascular Development.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Super-resolution ultrasound localization (UL) imaging enables microvascular visualization beyond the acoustic diffraction limit, but is limited by the short circulation time and uneven distribution of microbubbles. Here, we present photo-activated UL (PaUL) imaging using laser-triggered nanodroplets for super-resolved imaging with precise spatiotemporal control. We synthesized dual-contrast indocyanine green (ICG)-encapsulated perfluoropentane nanodroplets and developed a programmable activation and imaging sequence. PaUL imaging achieved 21 µm spatial resolution and enabled on-demand contrast generation by tuning laser fluence. Compared to conventional UL imaging, PaUL imaging provided 2.4× faster vascular reconstruction and 1.6× longer tracking lengths in hemodynamic mapping. Its extended circulation time allowed up to 3× more localization events across imaging windows exceeding 20 minutes. Overall, PaUL imaging offers flexible, high-resolution contrast and can be integrated with photoacoustic imaging to enhance multimodal capabilities. This technique holds promise for microvascular imaging and image-guided therapeutic applications such as targeted drug delivery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.