Evidence map›Paper›PMID 41605963›Full record

ArticleNPJ breast cancer2026

Adherence to oral endocrine therapy by menopausal status: post hoc insights from a remote monitoring randomized trial.

Ilana Graetz, Xin Hu, Rebecca A Krukowski, Janeane N Anderson, Edward Stepanski, Gregory Vidal, Teresa M Waters, Lee S Schwartzberg

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ breast cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03592771 (Communication App to Manage Symptoms and Improve Adjuvant Endocrine Therapy Adherence), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03592771 nacompletednot on this map

Communication App to Manage Symptoms and Improve Adjuvant Endocrine Therapy Adherence

TypeinterventionalSponsorEmory UniversityRan2018 to 2022Enrolled304ConditionsBreast Neoplasm FemaleArmsTHRIVE App, Tailored Feedback Messages
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ilana GraetzRollins School of Public Health, Emory University, Atlanta, GA, USA. ilana.graetz@emory.edu.
Xin HuRollins School of Public Health, Emory University, Atlanta, GA, USA.
Rebecca A KrukowskiUniversity of Virginia Cancer Center and School of Medicine, Charlottesville, VA, USA.
Janeane N AndersonDepartment of Community and Population Health, College of Nursing, University of Tennessee Health Science Center, Memphis, TN, USA.
Edward StepanskiOvation.io, Cambridge, MA, USA.
Gregory VidalWest Cancer Center and Research Institute, Germantown, TN, USA.
Teresa M WatersSchool of Public Health, Augusta University, Augusta, GA, USA.
Lee S SchwartzbergRenown Institute for Cancer and University of Nevada, Reno, Reno, NV, USA.

Funding

Effect of patient-provider sexual communication adjuvant endocrine therapy adherence, sexual dysfunction management, and sexual quality of life among Black women with breast cancerR01CA218155 · NCI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI GRAETZ, ILANA · 2017 to 2021
$2.3M
NCI NIH HHS R01 CA218155NIH HHS R01CA218155
6 · The paper itself

Abstract

Oral adjuvant endocrine therapy (AET) improves survival in hormone receptor-positive breast cancer, but younger, premenopausal women often struggle with adherence. In a post hoc analysis of a randomized trial (N = 304), app-based remote symptom monitoring improved 12-month AET adherence among premenopausal women (App-only: 53.9% vs. EUC: 25.0%), with no benefit for postmenopausal women. Findings suggest remote monitoring may help close adherence gaps in younger patients. Prospectively registered on ClinicalTrials.gov: NCT03592771.

Identifiers

PMID41605963
PMCPMC12953915

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.