Evidence map›Paper›PMID 41605894›Full record

ArticleLight, science & applications2026

Dual-channel high-speed functional photoacoustic microscopy with ultra-wide field of view.

Van Tu Nguyen, Carlos Taboada, Jesse Delia, Tri Vu, Luca Menozzi, Soon-Woo Cho, Jing Li, Nishad Jayasundara, Anthony DiSpirito, Junjie Yao

Abstract read
In one paragraph

Article in Light, science & applications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Photoacoustic Fingerprinting for Robust Molecular Imaging.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Van Tu Nguyen *Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.ORCID http://orcid.org/0000-0002-4913-438X
Carlos Taboada *Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA. carlos.a.taboada@vanderbilt.edu.
Jesse DeliaDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, 37232, USA.
Tri VuDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Luca MenozziDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.ORCID http://orcid.org/0000-0001-7542-1051
Soon-Woo ChoDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.ORCID http://orcid.org/0000-0002-5019-1429
Jing LiDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Nishad JayasundaraNicholas School of the Environment, Duke University, Durham, NC, 27713, USA.
Anthony DiSpiritoDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Junjie YaoDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA. junjie.yao@duke.edu.ORCID http://orcid.org/0000-0002-2381-706X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoacoustic microscopy (PAM) systems often face challenges in simultaneously achieving high speed, high resolution, high sensitivity, and a large field of view (FOV). To address this challenge, we have developed dual-channel PAM (DC-PAM) that can expand the FOV without compromising the imaging speed, detection sensitivity, or spatial resolution. DC-PAM has two identical, independent channels of laser excitation and acoustic detection. It exploits two facets of a single hexagon scanner to concurrently steer the dual excitation laser beams and the resultant acoustic waves. DC-PAM achieves an ultra-wide FOV of 22.5 × 24 mm² with a total functional imaging time of ~15 s. Proof-of-concept experiments were conducted using DC-PAM on freely-swimming zebrafish, hypoxia-challenged mice, and sleeping glassfrogs, all of which benefit from the large FOV and high imaging speed to track the dynamic and physiological processes at the whole-organ or whole-body level. These applications demonstrate the potential of DC-PAM for a wide range of biological studies.

Identifiers

PMID41605894
PMCPMC12852836

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.