Evidence map›Paper›PMID 41605865›Full record

ArticleGut microbes2026

Selvin Solis, Elaina M Maldonado, Subhankar Mukhopadhyay, Gwénaël Jan, José María Landete, Carlos Maluquer de Motes, Jorge Gutierrez-Merino

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Selvin SolisSchool of Biosciences, University of Surrey, Guildford, UK.
Elaina M MaldonadoSchool of Biosciences, University of Surrey, Guildford, UK.
Subhankar MukhopadhyaySchool of Immunology & Microbial Sciences, King's College London, London, UK.ORCID 0000-0002-7110-6473
Gwénaël JanSTLO, INRAE, Institut Agro, Rennes, France.ORCID 0000-0001-8694-3381
José María LandeteInstituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, Spain.ORCID 0000-0002-5147-3989
Carlos Maluquer de MotesSchool of Biosciences, University of Surrey, Guildford, UK.ORCID 0000-0003-4712-4601
Jorge Gutierrez-MerinoSchool of Biosciences, University of Surrey, Guildford, UK.ORCID 0000-0003-0088-0397

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiome plays a critical role in health, disease and immunity. To date, we have access to large datasets describing how the microbial diversity present in the gut correlates with many clinical conditions. However, the microbiome composition is taxonomically complex; influenced by many environmental factors; and variable between individuals and communities, thereby limiting functional and mechanistic insights into the microbiota‒host interactions. We are still unsure of the molecular mechanisms by which gut commensal microbes intrinsically possess to interact with the immune system and induce beneficial responses. This study has addressed this important question by revealing that only certain members of

Indexed as

Interferon Type ILactiplantibacillus plantarumNod2 Signaling Adaptor ProteinNucleotidyltransferasesAnimalscGAS-STING Signaling PathwayCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseCytosolHumansInnate Immunity RecognitionMacrophagesMembrane ProteinscGAS protein, humanCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseInterferon Type IMembrane ProteinsNOD2 protein, humanNod2 Signaling Adaptor ProteinNucleotidyltransferasescGASinterferonintracellular sensingLactobacillusNOD2probiotic bacteria

Identifiers

PMID41605865
PMCPMC12854382

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.