ReviewTrends in genetics : TIG2026
Reproductive phasiRNAs are the piRNAs of plants.
Review in Trends in genetics : TIG, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Presence and function of small RNAs during plant reproduction.RNA biology · 2026Review
- Article
- Reproductive phasiRNAs: At the core of small RNA-mediated male fertility in monocots.Plant communications · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Small RNAs are fundamental to gene expression regulation, with specialized classes playing critical roles in reproduction. This review compares animal PIWI-interacting RNAs (piRNAs) and plant reproductive phased small interfering RNAs (phasiRNAs), which show remarkable similarities. Both originate from Pol II-transcribed precursors but have distinct biogenesis pathways. piRNA processing in metazoans is Dicer-independent, involving PIWI-clade proteins for amplification via 'ping-pong' and phased cleavage. Reproductive phasiRNAs are Dicer-dependent and are initiated by miRNA-guided cleavage to generate phased sRNAs. A well-defined piRNA function is transposon silencing, but roles for nontransposon-targeting piRNAs and most reproductive phasiRNAs remain unresolved. Comparing these independently evolved systems reveals common strategies for reproductive success and highlights key unresolved questions regarding their molecular targets, functions, and evolutionary pressures that shaped them.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.