Evidence map›Paper›PMID 41605614›Full record

ArticleGut2026

Repositioning dual GLP-1/GIP receptor agonists for the treatment of colitis and colitis-associated tumourigenesis.

Bianca N Islam, Adrian Nguyen-Gomez, Kristina Williams, Kimberly Curry, Neha S Khandekar, Marcello Chieppa, Wei Xin, Theresa T Pizarro, Rui Wang, Fabio Cominelli

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bianca N IslamMedicine/Gastroenterology and Liver Disease, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID http://orcid.org/0000-0002-2124-1028
Adrian Nguyen-GomezDigestive Health Research Institute, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID http://orcid.org/0000-0002-7226-6428
Kristina WilliamsMedicine/Gastroenterology and Liver Disease, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID http://orcid.org/0009-0000-8885-7612
Kimberly CurrySurgery, Case Western Reserve University, Cleveland, Ohio, USA.ORCID http://orcid.org/0009-0006-8703-620X
Neha S KhandekarMedicine/Gastroenterology and Liver Disease, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID http://orcid.org/0009-0004-9244-5070
Marcello ChieppaUniversita del Salento, Lecce, Apulia, Italy.ORCID http://orcid.org/0000-0001-9819-0823
Wei XinPathology, University of South Alabama, Mobile, Alabama, USA.ORCID http://orcid.org/0000-0003-0987-0443
Theresa T PizarroPathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID http://orcid.org/0000-0003-3163-915X
Rui WangSurgery, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID http://orcid.org/0000-0001-5794-7201
Fabio CominelliMedicine/Gastroenterology and Liver Disease, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA fabio.cominelli@uhhospitals.org.ORCID http://orcid.org/0000-0002-1571-1548

Funding

TUMOR METABOLISM PROGRAMP30CA043703 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI Amar Desai · 1987 to 2026
$142.3M
The Cleveland Digestive Diseases Research Core Center (DDRCC)P30DK097948 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI AMITABH CHAK · 2015 to 2026
$15.6M
Role of LRG1 in colorectal cancer tumorigenesisR37CA278982 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI Rui Wang · 2024 to 2026
$1.1M
NCI NIH HHS P30 CA043703NCI NIH HHS R37 CA278982NIDDK NIH HHS P30 DK097948
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DIETARY - COLON CANCEREXPERIMENTAL COLITISINFLAMMATORY BOWEL DISEASE

Identifiers

PMID41605614
PMCPMC13528585

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.