Evidence map›Paper›PMID 41605578›Full record

ArticleBMJ open2026

Determinants for the implementation of a combined lifestyle intervention for patients with knee osteoarthritis and overweight: a qualitative study.

Priya Gharbaran, Nuria Ej Jansen, Inge Merkelbach, Marienke van Middelkoop, Dieuwke Schiphof

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Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Priya GharbaranGeneral Practice, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.
Nuria Ej JansenGeneral Practice, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0001-8804-9025
Inge MerkelbachErasmus School of Social and Behavioural Sciences / Behavioural Change, Erasmus Universiteit Rotterdam, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0003-2492-6871
Marienke van MiddelkoopGeneral Practice, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.
Dieuwke SchiphofGeneral Practice, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands d.schiphof@erasmusmc.nl.ORCID http://orcid.org/0000-0002-1293-6346

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLifestyle changes-such as adopting healthy nutrition and increasing physical activity-are essential for alleviating symptoms in patients with knee osteoarthritis (OA) and overweight, with weight loss being a key outcome of these changes. Since 2019, healthcare professionals (HCPs) in the Netherlands have been able to refer these patients to a reimbursed combined lifestyle intervention (CLI). This study aims to identify determinants affecting CLI implementation for individuals with knee OA and overweight from both patient and HCP perspectives.

designSemistructured interviews were conducted in a qualitative study with 23 individuals with knee OA and overweight and 16 HCPs (general practitioners (GPs) and lifestyle coaches). Interviews were transcribed verbatim and coded independently by two researchers using the updated Consolidated Framework for Implementation Research (CFIR).

settingPrimary care, including GPs and lifestyle coaches from the Greater Rotterdam region in the Netherlands.

participants23 individuals with knee OA and overweight and 16 HCPs (GPs and lifestyle coaches).

resultsDeterminants were explored within four CFIR domains: innovation, outer setting, inner setting and individuals. Key facilitators included recognition of the programme's potential, strong social support and positive participant-coach relationships. Major barriers involved the absence of an exercise component, financial constraints limiting its inclusion, scepticism among GPs about care quality, limited expertise of lifestyle coaches addressing OA-specific needs and difficulties adapting the programme to participants' diverse knowledge levels and health literacy.

conclusionsTo improve the implementation of the CLI for patients with knee OA, it is essential to incorporate a tailored exercise component, strengthen lifestyle coaches' expertise, address financial barriers and build trust among GPs through education and clear communication of programme outcomes. Tailoring the CLI to better meet participant needs is crucial to ensure its long-term effectiveness and sustainability as a treatment for individuals with knee OA and overweight. TRIAL REGISTERATION NUMBER: Netherlands Trial Registry (NL9355).

Indexed as

Life StyleOsteoarthritis, KneeOverweightAgedExerciseFemaleHumansMaleMiddle AgedNetherlandsPrimary Health CareQualitative ResearchBehaviourExerciseObesityPrimary CareQUALITATIVE RESEARCH

Identifiers

PMID41605578
PMCPMC12853553

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.