Evidence map›Paper›PMID 41604692›Full record

ArticleMolecular pharmaceutics2026

Paired Agent Imaging to Evaluate the Improvement of Affinity-Matured Nimotuzumab K4 and K5 Variants as EGFR-Detecting Optical Imaging Agents.

Wendy Bernhard, Kris Barreto, Yaima Tundidor, Darien Toledo, Kimberly A Jett, Gertrudis Rojas, C Ronald Geyer

Abstract read
In one paragraph

Article in Molecular pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wendy BernhardUniversity of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.
Kris BarretoUniversity of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.
Yaima TundidorCenter of Molecular Immunology, Play Municipality, Havana 11600, Cuba.ORCID 0000-0002-2500-2876
Darien ToledoCenter of Molecular Immunology, Play Municipality, Havana 11600, Cuba.
Kimberly A JettUniversity of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.
Gertrudis RojasCenter of Molecular Immunology, Play Municipality, Havana 11600, Cuba.
C Ronald GeyerUniversity of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.ORCID 0000-0003-1628-9665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular imaging is a useful tool for the

Indexed as

Antibodies, Monoclonal, HumanizedErbB ReceptorsMolecular ImagingOptical ImagingAnimalsBenzenesulfonatesCell Line, TumorFemaleHumansIndolesMiceMice, NudeXenograft Model Antitumor AssaysAntibodies, Monoclonal, HumanizedBenzenesulfonatesEGFR protein, humanErbB ReceptorsIndolesIRDye 800CWnimotuzumabEGFRfluorescent imagingIRDyenimotuzumabpaired agent imaging

Identifiers

PMID41604692
PMCPMC12958290

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.