ArticleJournal of medical Internet research2026
The Development and Use of AI Chatbots for Health Behavior Change: Scoping Review.
Article in Journal of medical Internet research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07612800 (Tailored Brain Health Insights Through Nurturing Knowledge-based Change - Stakeholder-driven, Human-centered, AI-powered Refinement for Prevention), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Tailored Brain Health Insights Through Nurturing Knowledge-based Change - Stakeholder-driven, Human-centered, AI-powered Refinement for Prevention (THINK-SHARP)
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Usability and User Experience Assessment of Health Care Conversational Agents Using Validated Subjective Instruments: Systematic Review and Comparative Analysis.JMIR human factors · 2026Pooled it
- Artificial Intelligence as a Personal Coach: A Narrative Review of Benefits and Risks in Educational and Health Contexts.Behavioral sciences (Basel, Switzerland) · 2026Review
- Designing for Autonomous Motivation: Qualitative Interview Study on Pre-Enrollment Preferences of Survivors of Cancer for Digital Health Behavior Change Programs.Journal of medical Internet research · 2026Article
- Body Image and Eating Disorder Education Chatbot, JEM, in Australia and Canada: First 6-Month Real-World Survey Evaluation.JMIR human factors · 2026Article
- Interpretative machine learning for predicting 60-day mortality in burn patients with suspected infection.World journal of emergency medicine · 2026Article
- The Development and Use of AI Chatbots for Health Behavior Change: Scoping Review.Journal of medical Internet research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArtificial intelligence (AI) chatbots are technologies that facilitate human-computer interaction through communication in a natural language format. By increasing cost-effectiveness, interaction, autonomy, personalization, and support, mobile health interventions can benefit health behavior change and make it more natural and intuitive.
objectiveThis study aimed to provide an up-to-date and practical overview of how text-based AI chatbots are designed, developed, and evaluated across 8 health behaviors, including their roles, theoretical foundations, health behavior change techniques, technology development workflow, and performance validation framework.
methodsIn accordance with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) framework, relevant studies published before March 2024 were identified from 9 bibliographic databases (ie, PubMed, CINAHL, MEDLINE, Embase, Web of Science, Scopus, APA PsycINFO, IEEE Xplore, and ACM Digital Library). Two stages (ie, title and abstract screening followed by full-text screening) were conducted to screen the eligibility of the papers via Covidence software. Finally, we extracted the data via Microsoft Excel software and used a narrative approach, content analysis, and evidence map to synthesize the reported results.
resultsOur systematic search initially identified 10,508 publications, 43 of which met our inclusion criteria. AI chatbots primarily served 2 main roles: routine coach (27/43, 62.79%) and on-demand assistant (12/43, 27.91%), while 4 studies (4/43, 9.30%) integrated both roles. Frameworks like cognitive behavioral therapy (13/24, 54.17%) and behavior change techniques, such as goal setting, feedback and monitoring, and social support, guided the development of theory-driven AI chatbots. Noncode platforms (eg, Google Dialogflow and IBM Watson) integrated with social messaging platforms (eg, Facebook Messenger) were commonly used to develop AI chatbots (23/43, 53.49%). AI chatbots have been evaluated across 4 domains: technical performance (17/43, 39.53%), usability (17/43, 39.53%), engagement (37/43, 86.05%), and health behavior change (33/43, 76.74%). Evidence for health behavior changes remains exploratory but promising. Among 33 studies with 120 comparisons, 81.67% (98/120) showed positive outcomes, though only 35.83% (43/120) had moderate or larger effects (Hedges g or odds ratio or Cohen d>0.5). Most involved nonclinical (36/43, 83.72%) and adults (23/43, 53.49%), and a few were randomized controlled trials (14/43, 32.56%). Benefits were mainly seen in physical activity, smoking cessation, stress management, and diet, with limited evidence for other behaviors. Findings were inconsistent regarding the influence of long-term effects, intervention duration, modality, and engagement on health behavior change outcomes.
conclusionsThe exploratory synthesis provides a roadmap for developing and evaluating AI chatbots in health behavior change, highlighting the need for further research on cost, implementation outcomes, and underexplored behaviors such as sleep, weight management, sedentary behavior, and alcohol use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.