Evidence map›Paper›PMID 41604455›Full record

ArticleMolecular biology of the cell2026

TEP-1, a glial thioester protein is required for cilia organization and intraflagellar transport in ensheathed sensory neurons in

Yumiko Oshima, Yaminisree Nagidi, Maya E Moorthy, Jonathon Heier, Joanne A Matsubara, Jeff Hardin, Martin Flajnik, Bruce E Vogel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular biology of the cell, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Yumiko OshimaDepartment of Pharmacology and Physiology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.
Yaminisree NagidiDepartment of Pharmacology and Physiology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.
Maya E MoorthyDepartment of Pharmacology and Physiology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.
Jonathon HeierDepartment of Integrative Biology, University of Wisconsin Madison, Madison, WI 53706.
Joanne A MatsubaraDepartment of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC V5Z 3N9, Canada.
Jeff HardinDepartment of Integrative Biology, University of Wisconsin Madison, Madison, WI 53706.
Martin FlajnikDepartment of Microbiology and Immunology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.
Bruce E VogelDepartment of Pharmacology and Physiology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.ORCID 0000-0002-2576-3843

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Regulation of dynamic actin networks during epithelial morphogenesisR35GM145312 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Jeffrey D Hardin · 2022 to 2026
$3.0M
Molecular Genetics of a Complement Factor H homologR01EY032868 · NEI · UNIVERSITY OF MARYLAND BALTIMORE · PI VOGEL, BRUCE E · 2021 to 2025
$1.9M
NEI NIH HHS R01 EY032868NIGMS NIH HHS R35 GM145312NIH HHS P40 OD010440
6 · The paper itself

Abstract

Age-related macular degeneration (AMD), the leading cause of blindness in the elderly, is characterized by progressive degeneration of retinal photoreceptors. Traditional disease models suggest that defective repression of thioester protein C3 activity by complement factor H (CFH) is a major contributor to pathogenesis in AMD and a related disease, early-onset drusen maculopathy (EODM). Our previous study identified novel functions for human CFH and

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsCiliaFlagellaSensory Receptor CellsAnimalsComplement C3Complement Factor HHumansMacular DegenerationNeurogliaCaenorhabditis elegans ProteinsComplement C3Complement Factor H

Identifiers

PMID41604455
PMCPMC12911856

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.