Evidence map›Paper›PMID 41604268›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Germline fate determination by a single ARGONAUTE protein in

Viktoriia Bukhanets, Rita A Batista, Fabian B Haas, Rémy Luthringer, Jumana Kushkush, Min Zheng, Katharina Hipp, Vikram Alva, Claudia Martinho, Susana M Coelho

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Viktoriia Bukhanets *Department of Algal Development and Evolution, Max Planck Institute for Biology, Tübingen 72076, Germany.
Rita A Batista *Department of Algal Development and Evolution, Max Planck Institute for Biology, Tübingen 72076, Germany.ORCID 0000-0002-2083-4622
Fabian B Haas *Department of Algal Development and Evolution, Max Planck Institute for Biology, Tübingen 72076, Germany.ORCID 0000-0002-7711-5282
Rémy LuthringerDepartment of Algal Development and Evolution, Max Planck Institute for Biology, Tübingen 72076, Germany.
Jumana KushkushDepartment of Algal Development and Evolution, Max Planck Institute for Biology, Tübingen 72076, Germany.
Min ZhengDepartment of Algal Development and Evolution, Max Planck Institute for Biology, Tübingen 72076, Germany.ORCID 0009-0009-8194-0574
Katharina HippElectron Microscopy Core Facility, Max Planck Institute for Biology, Tübingen 72076, Germany.ORCID 0000-0002-1493-9698
Vikram AlvaDepartment of Protein Evolution, Max Planck Institute for Biology, Tübingen 72076, Germany.ORCID 0000-0003-1188-473X
Claudia MartinhoDepartment of Algal Development and Evolution, Max Planck Institute for Biology, Tübingen 72076, Germany.
Susana M CoelhoDepartment of Algal Development and Evolution, Max Planck Institute for Biology, Tübingen 72076, Germany.ORCID 0000-0002-9171-2550

Funding

Bettencourt Foundation sEC | European Research Council (ERC) sGordon and Betty Moore Foundation (GBMF) s
6 · The paper itself

Abstract

ARGONAUTE (AGO) proteins are a highly conserved family of RNA-binding proteins that play central roles in gene regulation and developmental processes across eukaryotes. Although AGO family members have been extensively studied in animals and plants, where they are typically encoded by multiple genes, their function in brown algae, a diverse and complex group of multicellular algae, remains largely unknown. Here, we show that the genomes of several brown algae encode only a single AGO protein, containing the conserved functional domains characteristic of the family. Using the model brown alga

Indexed as

Argonaute ProteinsGerm CellsPhaeophyceaeMicroRNAsArgonaute ProteinsMicroRNAsArgonauteEctocarpusgermlinemutantsexual reproduction

Identifiers

PMID41604268
PMCPMC12867755

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.