Evidence map›Paper›PMID 41604263›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Drospondin, a glial glycoprotein with similarities to human Reelin/F-spondin, contributes to

Francisca Rojo-Cortés, Candy Roa-Siegfried, Paula Amado-Hinojosa, Nicolás Fuenzalida-Uribe, María-Constanza González-Ramírez, Raúl Chacón-Álvarez, Isidora Almonacid-Torres, Serge Birman, Lindsey D Goodman, Oguz Kanca and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Frontiers in cell and developmental biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Francisca Rojo-CortésLaboratorio de Neurogenética de la Conducta, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.ORCID 0000-0003-2332-8423
Candy Roa-SiegfriedLaboratorio de Neurogenética de la Conducta, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.
Paula Amado-HinojosaLaboratorio de Neurogenética de la Conducta, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.
Nicolás Fuenzalida-UribeDepartment of Biology, University of Puerto Rico, Rio Piedras, San Juan 00931, Puerto Rico.ORCID 0000-0002-4975-7667
María-Constanza González-RamírezLaboratorio de Neurodesarrollo, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.
Raúl Chacón-ÁlvarezLaboratorio de Neurodesarrollo, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.ORCID 0009-0003-4533-2770
Isidora Almonacid-TorresLaboratorio de Neurogenética de la Conducta, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.
Serge BirmanGenes Circuits Rhythms and Neuropathology, Brain Plasticity Unit, Unité Mixte de Recherche 8249, Centre National de la Recherche Scientifique, École Supérieure de Physique et de Chimie Industrielles de la Ville de Paris, Paris Sciences et Lettres University, Paris 75005, France.
Lindsey D GoodmanDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030.
Oguz KancaDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030.
Carlos OlivaLaboratorio de Neurodesarrollo, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.ORCID 0000-0002-9551-149X
María Paz MarzoloLaboratorio de Tráfico Intracelular y Señalización, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.ORCID 0000-0002-2328-2464
Jorge M CampusanoLaboratorio de Neurogenética de la Conducta, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.ORCID 0000-0001-5254-8340

Funding

A Comprehensive Resource for Manipulating the Drosophila GenomeR24OD031447 · OD · BAYLOR COLLEGE OF MEDICINE · PI HUGO J BELLEN, Oguz Kanca · 2021 to 2026
$5.2M
Mutidisciplinary Training;Brain Disorders &DevelopmentT32NS043124 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI SWANN, JOHN WILLIAM · 2002 to 2021
$4.6M
ANID | Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT) 1231556ANID | Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT) 1231685ANID | Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT) 1250202HHS | NIH | National Institute on Aging (NIA) R24OD031447NIH HHS R24 OD031447NINDS NIH HHS T32 NS043124
6 · The paper itself

Abstract

Reelin is a secreted glycoprotein with roles in the development of the mammalian neocortex, hippocampus, and cerebellum. This vertebrate signaling molecule also contributes to adult brain function. Mammalian Reelin increases the complexity of

Indexed as

BrainCell Adhesion Molecules, NeuronalDrosophila melanogasterDrosophila ProteinsExtracellular Matrix ProteinsGlycoproteinsNerve Tissue ProteinsNeurogliaSerine EndopeptidasesAnimalsHumansReelin ProteinCell Adhesion Molecules, NeuronalDrosophila ProteinsExtracellular Matrix ProteinsGlycoproteinsNerve Tissue ProteinsReelin ProteinRELN protein, humanSerine Endopeptidasesbrain developmentCG17739DrosophilaF-spondinReelin

Identifiers

PMID41604263
PMCPMC12867693

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.