Evidence map›Paper›PMID 41604097›Full record

Observational studyEuropean geriatric medicine2026

Feeding-related hospitalizations and outcomes in advanced dementia.

Ana Rita Ramalho, Maria João Rocha, José Artur Magalhães, Nuno Santos, Isabel Santana, Manuel Teixeira Veríssimo, Lèlita Santos

Abstract readObservational Study
In one paragraph

Observational study in European geriatric medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ana Rita RamalhoInternal Medicine Department, Hospitais da Universidade de Coimbra, Unidade Local de Saúde de Coimbra, Coimbra, Portugal. anaritaramalho@ulscoimbra.min-saude.pt.ORCID http://orcid.org/0000-0001-7968-8706
Maria João RochaInternal Medicine Department, Hospitais da Universidade de Coimbra, Unidade Local de Saúde de Coimbra, Coimbra, Portugal.
José Artur MagalhãesInternal Medicine Department, Hospitais da Universidade de Coimbra, Unidade Local de Saúde de Coimbra, Coimbra, Portugal.
Nuno SantosInternal Medicine Department, Hospitais da Universidade de Coimbra, Unidade Local de Saúde de Coimbra, Coimbra, Portugal.
Isabel SantanaFaculty of Medicine, University of Coimbra, Coimbra, Portugal.ORCID http://orcid.org/0000-0002-8114-9434
Manuel Teixeira VeríssimoFaculty of Medicine, University of Coimbra, Coimbra, Portugal.ORCID http://orcid.org/0000-0002-2793-2129
Lèlita SantosInternal Medicine Department, Hospitais da Universidade de Coimbra, Unidade Local de Saúde de Coimbra, Coimbra, Portugal.ORCID http://orcid.org/0000-0002-0761-5097

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDementia is a chronic disease characterized by progressive and mostly irreversible cognitive and functional decline. Advanced dementia is linked to high mortality and morbidity, with over 85% of patients experiencing feeding-related problems. Care should focus on comfort and quality of life, with medical societies recommending against tube feeding, supporting instead careful hand feeding. However, awareness among healthcare professionals regarding tube indications and complications remains limited. PURPOSE: To identify the frequency of hospitalizations related to feeding problems, analyze healthcare professionals' attitudes, and compare the outcomes of patients with and without tube feeding.

methodsThis retrospective, observational cohort study analyzed patients aged ≥ 65 years with advanced dementia admitted to Internal Medicine Department of Coimbra's Healthcare Integrated Delivery System between January 1 and March 31, 2023. Sociodemographic, clinical, feeding-related data, along with complications, mortality, and readmissions, were collected and analyzed via STATA.

resultsOf the 1,735 admissions, 178 patients met the inclusion criteria (mean age 86; 64.5% female). Respiratory illnesses were the primary diagnosis (56.7%), and in-hospital mortality rate was 23%. Feeding-related hospitalizations occurred in 17.4% of the patients, mainly due to aspiration. At discharge, 102 patients had no feeding tube (Group A), and 76 did (Group B). Group B had significantly higher complication rates at one year than did Group A, without a survival benefit.

conclusionOur findings demonstrate that feeding-related complications also occur in patients receiving enteral tube feeding, without increasing survival or reducing complications and underscore the need for professional training and individualized evidence-based care in advanced dementia.

Indexed as

DementiaEnteral NutritionHospitalizationAgedAged, 80 and overFemaleHospital MortalityHumansMaleQuality of LifeRetrospective StudiesAdvanced dementiaCareful hand feedingDifficulty eatingEnteral tube feedingMortalityNasogastric tube feeding

Identifiers

PMID41604097
PMCPMC13109124

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.