ArticleTransgenic research2026
Overexpression of Forsythia intermedia pinoresinol lariciresinol reductase gene in Sesamum indicum increases secoisolariciresinol diglucoside content.
Article in Transgenic research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Sesame (Sesamum indicum), an important oilseed crop, is well known for its therapeutic values. It is one of the richest sources of polyunsaturated fatty acids and health beneficiary lignans. However, nutraceutical potential is restricted due to the presence of secoisolariciresinol diglucoside (SDG), a potent anticarcinogen, in imperceptible amount (~ 0.03 mg/25 g of seeds). Consequently, a logical strategy was implemented to augment the SDG content in sesame by heterologous expression of the pinoresinol-lariciresinol reductase (Fiplr) gene from Forsythia intermedia. Four individual transgenic lines were generated by Agrobacterium-mediated transformation of pCAMBIA/Fiplr gene cassette into sesame and was further confirmed by PCR and Southern blot analyses. Among the Individual transgenic lines, PT
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