ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026
Neurodevelopmental outcomes in children with craniosynostosis: a retrospective cross-sectional analysis.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Methodological determinants and prevalence of elevated intracranial pressure in isolated single-suture craniosynostosis: a systematic review and meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Pooled it
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6 authors.
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Abstract
objectiveThis retrospective study evaluated neurodevelopmental outcomes including cognitive, motor, language, and social functioning in children with craniosynostosis and examined the influence of suture type, syndromic status, timing of surgery, and raised intracranial pressure.
methodsA cross-sectional retrospective study of 150 children (ages 3-12) with craniosynostosis was conducted using medical records and standardized neurodevelopmental tests. Statistical analyses included t-tests, chi-square tests, and multivariate regression.
resultsMetopic synostosis was associated with slightly lower language and higher social impairment scores, but these differences were not significant after adjustment. Surgery before 9 months conferred ~5-point advantages in cognitive and motor outcomes, particularly in sagittal and coronal synostosis. Raised intracranial pressure, present in 13%, was linked to poorer outcomes.
conclusionNeurodevelopmental outcomes in children with craniosynostosis are primarily influenced by syndromic status, timing of surgery, and raised intracranial pressure rather than suture type alone. Early surgical intervention before 9 months has been associated with improved cognitive and motor outcomes, supporting early referral and intervention.
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