Evidence map›Paper›PMID 41603931›Full record

Trial reportOperative Orthopadie und Traumatologie2026

[Surgical management of juvenile and aneurysmal bone cysts in children and adolescents : Curettage, ceramic bone graft substitution and adjuvants].

Sven-Oliver Dietz, Beatrice Jung, Michael Nienhaus, Frank Traub, Erol Gercek

Abstract readClinical TrialEnglish Abstract
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In one paragraph

Trial report in Operative Orthopadie und Traumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sven-Oliver DietzZentrum für Orthopädie und Unfallchirurgie, Universitätsmedizin Mainz, Johannes Gutenberg - Universität Mainz, Langenbeckstr. 1, 55131 Mainz, Mainz, Deutschland. sven-oliver.dietz@unimedizin-mainz.de.
Beatrice JungZentrum für Orthopädie und Unfallchirurgie, Universitätsmedizin Mainz, Johannes Gutenberg - Universität Mainz, Langenbeckstr. 1, 55131 Mainz, Mainz, Deutschland.
Michael NienhausZentrum für Orthopädie und Unfallchirurgie, Universitätsmedizin Mainz, Johannes Gutenberg - Universität Mainz, Langenbeckstr. 1, 55131 Mainz, Mainz, Deutschland.
Frank TraubZentrum für Orthopädie und Unfallchirurgie, Universitätsmedizin Mainz, Johannes Gutenberg - Universität Mainz, Langenbeckstr. 1, 55131 Mainz, Mainz, Deutschland.
Erol GercekZentrum für Orthopädie und Unfallchirurgie, Universitätsmedizin Mainz, Johannes Gutenberg - Universität Mainz, Langenbeckstr. 1, 55131 Mainz, Mainz, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of treating juvenile (UBC) and aneurysmal bone cysts (ABC) is complete defect filling with subsequent bony consolidation, restoration of stability, pain reduction, and minimization of recurrence risk. INDICATIONS: Symptomatic or pathologic fractures due to confirmed UBC or ABC based on imaging and/or histology. CONTRAINDICATIONS: Suspected malignancy based on clinical or radiologic findings. SURGICAL TECHNIQUE: After fluoroscopic localization, the lesion is exposed via a tissue-sparing approach. The cyst wall is opened, and complete curettage is performed. The defect is filled with ceramic bone substitute and/or allogeneic cancellous bone soaked in methylprednisolone (UBC) or polidocanol (ABC). In ABC, the cyst lining is completely removed. In UBC, curettage combined with elastic-stable intramedullary nailing (ESIN) for stabilization is frequently sufficient. POSTOPERATIVE MANAGEMENT: Fractures are managed like nonpathologic fractures. Radiographic follow-up is performed at 4, 12, 26, and 52 weeks. If ABCs fail to respond, repeated percutaneous polidocanol injections are administered.

resultsIn a cohort of 44 patients (22 UBC, 23 ABC), after a follow-up of up to 6 years, 82% achieved a favorable radiological outcome (Capanna 1-2). Recurrence with refracture occurred in 4 patients after ESIN removal. The overall complication rate was low.

Indexed as

Bone Cysts, AneurysmalBone SubstitutesBone TransplantationCeramicsCurettageAdolescentChildChild, PreschoolCombined Modality TherapyFemaleHumansMaleMethylprednisolonePolidocanolPolyethylene GlycolsTreatment OutcomeBone SubstitutesMethylprednisolonePolidocanolPolyethylene GlycolsBone substituteCurettageGrowth disordersPolidocanolSpontaneous fractures

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.