ReviewLab on a chip2026
The evolution of nanopore measurements: from biological out-of-plane pores to plastic in-plane pores.
Review in Lab on a chip, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Microfluidics for Blood Disorders and Hematological Disease Monitoring and Modeling.International journal of molecular sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Nanopore sensing provides an ideal strategy for the label-free detection of single molecules in a variety of application scenarios. Working under the principle of resistive pulse sensing (RPS), nanopores consist of constrictions with sub-100 nm dimensions to enable single-molecule resolution by matching pore size to target dimensions (scaling); the optimal signal-to-noise ratio (SNR) results when the electrically biased pore is comparable in size to the molecule to be analyzed. When single molecules are electrokinetically transported through such remarkably small pores, they temporarily disturb the flux of ions moving through them, generating unique signals. These signals vary based upon the molecules' shape, size, orientation, and other physicochemical properties. Nanopores are generally divided into two main categories owing to their fabrication approach and material: biological and solid state. While biological nanopores have been the dominant sensor format due to their exceptionally small size, solid-state nanopores can demonstrate high performance characteristics attributed to their rigidity, stability, and high versatility in shape, material, and configuration. This review will explore the state-of-the-art in biological and solid-state nanopores and their abilities to detect and identify single biomolecules in a label-free manner. We will also review two topographical configurations of nanopore sensors; in-plane and out-of-plane sensors. The evolution of nanopore sensing will be reviewed, starting with out-of-plane biological sensors and progressing to in-plane sensors fabricated in plastics
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.