Evidence map›Paper›PMID 41603756›Full record

ArticleExperimental physiology2026

Quantifying skin microvascular function responses to distinct forms of heat stress in humans using optical coherence tomography.

Kristanti W Wigati, Robert A McLaughlin, Harrison T Caddy, Howard H Carter, Louise H Naylor, Daniel J Green

Abstract read
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kristanti W WigatiSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, Western Australia, Australia.
Robert A McLaughlinSchool of Biomedicine, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia.
Harrison T CaddySchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, Western Australia, Australia.
Howard H CarterSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, Western Australia, Australia.
Louise H NaylorSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, Western Australia, Australia.
Daniel J GreenSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, Western Australia, Australia.

Funding

Forrest Research Foundation ScholarshipNational Heart Foundation of Australia 107281Scholarship for International Research Fees and a University Post Graduate Award
6 · The paper itself

Abstract

Optical coherence tomography (OCT) enables visualization and quantification of the cutaneous microvasculature, yet no study has compared responses to distinct forms of heating in humans. We hypothesized that local skin heating (LH) would evoke larger responses in microvascular diameter, velocity, flow and density than passive whole-body heating (PH) or heated exercise (HE), and that HE responses would exceed PH. Twelve healthy young adults completed four interventions: baseline (33°C; BL), LH, PH (seated) and HE (ergometer cycling) in a climatic chamber (50 min, 40°C, 50% relative humidity). OCT was used to quantify microvascular variables immediately after each intervention. Microvascular responses differed across conditions (P < 0.001). LH induced the largest responses in all OCT indices (all P < 0.001): diameter (67 µm), velocity (195 µm s

Indexed as

heat exposureoptical coherence tomographyskin microvasculature

Identifiers

PMID41603756
PMCPMC13394450

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.