ArticlemSphere2026
Gut microbiota and parasite dynamics in an Amazonian community undergoing urbanization in Colombia.
Sebastián Díaz, Amie J Eisfeld, Mónica Palma-Cuero, Nathalie Dinguirard, Leah A Owens, Karl A Ciuoderis, Laura S Pérez-Restrepo, John D Chan, Tony L Goldberg, Jessica L Hite and 4 more
Abstract read
In one paragraphArticle in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
14 authors.
Sebastián DíazUW-GHI One Health Colombia, Universidad Nacional de Colombia, Medellín, Colombia.
Amie J EisfeldDepartment of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-2231-3107 Mónica Palma-CueroLaboratorio de Salud Pública Departamental del Amazonas, Grupo de Estudios en Salud Pública de la Amazonía, Leticia, Colombia.
Nathalie DinguirardDepartment of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Leah A OwensDepartment of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Karl A CiuoderisUW-GHI One Health Colombia, Universidad Nacional de Colombia, Medellín, Colombia.
Laura S Pérez-RestrepoUW-GHI One Health Colombia, Universidad Nacional de Colombia, Medellín, Colombia.
John D ChanDepartment of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-4986-972X Tony L GoldbergDepartment of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-3962-4913 Jessica L HiteDepartment of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Juan Pablo Hernandez-OrtizUW-GHI One Health Colombia, Universidad Nacional de Colombia, Medellín, Colombia.
Yoshihiro KawaokaDepartment of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-5061-8296 Mostafa ZamanianDepartment of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-9233-1760 Funding
Parasitology and Vector Biology Training ProgramT32AI007414 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI Lyric Colleen Bartholomay · 1992 to 2026
$4.5MMolecular mechanisms controlling secretion in filarial nematode parasitesR01AI151171 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI Mostafa Zamanian · 2020 to 2026
$2.4MComprehensive characterization of parasite and commensal assemblages in humansR21AI163592 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI GOLDBERG, TONY L. · 2022 to 2023
$428kNIH HHS R01AI151171NIH HHS R21AI163592NIH HHS T32AI007414
6 · The paper itselfAbstract
Studies on human gut microbiota have recently highlighted a significant decline in bacterial diversity associated with urbanization, driven by shifts toward processed diets, increased antibiotic usage, and improved sanitation practices. This phenomenon has been largely overlooked in the Colombian Amazon, despite rapid urbanization in the region. In this study, we investigate the composition of gut bacterial microbiota and intestinal protozoa and soil-transmitted helminths (STHs) in both urban and rural areas of Leticia, located in the southern Colombian Amazon. Despite their geographic proximity, the urban population is predominantly non-indigenous, while indigenous communities mostly inhabit the rural area, resulting in notable lifestyle differences between the two settings. Our analyses reveal a reduction in bacterial families linked to non-processed diets, such as
Indexed as
BacteriaGastrointestinal MicrobiomeUrbanizationAnimalsColombiaFecesHelminthsHumansRural PopulationUrban PopulationAmazonColombiahelminthsmicrobiomeprotozoa
Identifiers
PMID41603631
PMCPMC12931277
What OpenQuestion holds
Textmetadata
LicenceCC BY
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