Evidence map›Paper›PMID 41603463›Full record

ArticleSICOT-J2026

A systematic review of radiological outcomes and implant positioning in robotic-assisted functionally aligned robotic total knee arthroplasty.

Vasileios Giovanoulis, Angelo V Vasiliadis, Eleftherios Tsiridis, Luca Andriollo, Pietro Gregori, Konstantinos Dretakis, Christos Koutserimpas, Sébastien Lustig

Abstract read
In one paragraph

Article in SICOT-J, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vasileios GiovanoulisOrthopaedics Surgery and Sports Medicine Department, Hôpital de la Croix-Rousse, Lyon, France - Third Academic Department of Orthopaedics, Papageorgiou General Hospital, Thessaloniki 56403, Greece - Orthopedic Surgery Department, Lyon Ortho Clinic, Clinique de la Sauvegarde, Lyon, France.
Angelo V VasiliadisOrthopaedics Surgery and Sports Medicine Department, Hôpital de la Croix-Rousse, Lyon, France.
Eleftherios TsiridisThird Academic Department of Orthopaedics, Papageorgiou General Hospital, Thessaloniki 56403, Greece.
Luca AndriolloOrthopaedics Surgery and Sports Medicine Department, Hôpital de la Croix-Rousse, Lyon, France - Ortopedia e Traumatologia, Fondazione Poliambulanza Istituto Ospedaliero, Via Bissolati 57, 25124 Brescia, Italy.
Pietro GregoriOrthopaedics Surgery and Sports Medicine Department, Hôpital de la Croix-Rousse, Lyon, France - Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.
Konstantinos DretakisSecond Department of Orthopaedics, Hygeia General Hospital of Athens, Greece.
Christos KoutserimpasOrthopaedics Surgery and Sports Medicine Department, Hôpital de la Croix-Rousse, Lyon, France - Second Department of Orthopaedics, Hygeia General Hospital of Athens, Greece - School of Health Rehabilitation Sciences, University of Patras, Greece.
Sébastien LustigOrthopaedics Surgery and Sports Medicine Department, Hôpital de la Croix-Rousse, Lyon, France - IFSTTAR, LBMC UMR_T9406, Univ Lyon, Claude Bernard Lyon 1 University, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFunctional alignment (FA) or functional knee positioning is a patient-specific strategy for total knee arthroplasty (TKA) that utilizes robotics to balance coronal, sagittal, and axial planes while preserving joint-line orientation and soft-tissue tension within predefined guardrails. Although early clinical outcomes are encouraging, the radiographic profile and workflow consistency of robotic FA have not been clearly synthesized.

methodsIn accordance with PRISMA guidelines, English-language studies of primary robotic FA-TKA with ≥2-year follow-up were searched. Eligible designs included RCTs, prospective/retrospective cohorts, and large case series (≥50 patients). Information on pre- and postoperative coronal alignment [hip-knee-ankle angle (HKA), lateral distal femoral angle (LDFA), medial proximal tibial angle (MPTA)], component positioning (femoral valgus/rotation/flexion; tibial varus/rotation/slope), and explicit FA workflow boundaries (guardrails) was extracted.

resultsTwenty-one cohorts (5,360 knees) reported at least one radiographic or workflow endpoint. Preoperatively, the predominant deformity was varus. Postoperatively, limb alignment converged near neutral: HKA clustered around 178-179.5°, with LDFA ~89-91° and MPTA ~87-89°. Component positions were tightly distributed within FA targets: femoral valgus ≈ 0.5-1.5°, tibial varus ≈ ~3°, femoral flexion ~6-9°, and tibial slope ~0-3°; tibial rotation was overwhelmingly referenced to Akagi's line, and femoral rotation to the TEA in most series. Reported guardrails showed strong convergence: typical workflows included femoral valgus -3° to +6°, tibial varus 0-6°, tibial slope 0-3°, and femoral ER ~3-6° to TEA. Across cohorts, achieved radiographs closely tracked these limits, indicating high adherence and reproducibility. Most observational studies had a moderate risk of bias; the lone RCT was low risk. DISCUSSION: Robotic FA-TKA delivers a radiographic profile with slight femoral valgus and modest tibial varus, while keeping components within narrow, pre-specified guardrails. LEVEL OF EVIDENCE: Level III, systematic review and meta-analysis.

Indexed as

Component positioningFunctional alignmentFunctional positioningRobotic-assisted TKATotal knee arthroplasty

Identifiers

PMID41603463
PMCPMC12849696

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.