Evidence map›Paper›PMID 41603416›Full record

Trial reportJournal of studies on alcohol and drugs2026

Brief Intervention Versus More Extensive Treatment for Alcohol Use Disorder (AUD): Testing the Comparability Hypothesis.

Patrick R Clifford, Stephen A Maisto, Christine M Davis, Robert L Stout, Marc L Steinberg

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Journal of studies on alcohol and drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patrick R CliffordSchool of Public Health, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Stephen A MaistoDepartment of Psychology, Syracuse University, Syracuse, New York.
Christine M DavisSchool of Public Health, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Robert L StoutPacific Institute for Research and Evaluation, Quantitative Capabilities Collaboration, Beltsville, Maryland.
Marc L SteinbergRobert Wood Johnson Medical School, Rutgers, The State University of New Jersey, Piscataway, New Jersey.

Funding

AUD Brief Interventions: Testing the Comparability Hypothesis and Purported MoBCR01AA022330 · NIAAA · RBHS-SCHOOL OF PUBLIC HEALTH · PI CLIFFORD, PATRICK R. · 2014 to 2018
$2.5M
RESEARCH PROTOCOLS AND ALCOHOL TREATMENT OUTCOMESR01AA012191 · NIAAA · UNIV OF MED/DENT NJ-SCH OF PUBLIC HEALTH · PI CLIFFORD, PATRICK R · 2000 to 2003
$1.3M
NIAAA NIH HHS R01 AA012191NIAAA NIH HHS R01 AA022330
6 · The paper itself

Abstract

objectiveThere is a substantial literature indicating that brief interventions (BIs) for alcohol use disorder (AUD) are as effective as more extensive treatments. The research assessment reactivity literature, however, suggests that the protocols used to study AUD treatments can have clinical efficacy, which may account for the observed findings. The purpose of this research was to experimentally investigate the moderation of AUD treatment effects by AUD assessment protocols.

methodParticipants were recruited from the community via advertisements (e.g., Facebook, mail, flyers). Eligible participants, providing informed consent, were randomized to one of four research conditions resulting from a two (Intervention: Motivational Enhancement Therapy [MET] or Cognitive Behavioral Coping Skills Therapy [CBT]) by two (Assessment: infrequent-alcohol/drug focused or frequent-comprehensive) factorial design and followed for 15 months after baseline assessment.

resultsAcross the entire sample, the proportion of abstinence days increased from 21.6% at baseline to 62.4% during follow-up months 13-15, and the proportion of heavy drinking days decreased from 64.9% at baseline to 18.1% during follow-up months 13-15. Although the hypothesized interaction "intervention by assessment condition" was not supported, main effects were detected for assessment condition, such that individuals assigned to the alcohol/drug-focused assessment conditions reported greater abstinence and fewer heavy drinking days than their counterparts assigned to the comprehensive assessment conditions.

conclusionsRobust BIs, such as MET, appear to yield drinking outcomes comparable to those of more extensive AUD treatments, such as CBT. In addition, reactivity to research assessments contributed to reduced alcohol use, and these effects appear to be contingent on intervention and participant characteristics.

Indexed as

AlcoholismAlcohol-Related DisordersCognitive Behavioral TherapyMotivational InterviewingPsychotherapy, BriefAdultCoping SkillsFemaleFollow-Up StudiesHumansMaleMiddle AgedTreatment Outcome

Identifiers

PMID41603416
PMCPMC12965277

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.