Evidence map›Paper›PMID 41603352›Full record

ArticleeLife2026

Mast cells promote pathology and susceptibility in tuberculosis.

Ananya Gupta, Vibha Taneja, Javier Rangel-Moreno, Nilofer Naqvi, Abhimanyu, Yun Tao, Mushtaq Ahmed, Kuldeep Singh Chauhan, Daniela Trejo-Ponce de Leon, Gustavo Ramírez-Martínez and 5 more

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Ananya Gupta *Department of Microbiology, The University of Chicago, Chicago, United States.ORCID https://orcid.org/0000-0001-7917-7877
Vibha Taneja *Department of Microbiology, The University of Chicago, Chicago, United States.ORCID https://orcid.org/0009-0002-9849-360X
Javier Rangel-MorenoDivision of Allergy, Immunology and Rheumatology, Department of Medicine, University of Rochester Medical Center, Rochester, United States.ORCID https://orcid.org/0000-0002-9738-1182
Nilofer NaqviDepartment of Microbiology, The University of Chicago, Chicago, United States.ORCID https://orcid.org/0000-0002-9566-0153
AbhimanyuDepartment of Microbiology, The University of Chicago, Chicago, United States.ORCID https://orcid.org/0000-0001-7888-8722
Yun TaoDepartment of Microbiology, The University of Chicago, Chicago, United States.
Mushtaq AhmedDepartment of Microbiology, The University of Chicago, Chicago, United States.
Kuldeep Singh ChauhanDepartment of Microbiology, The University of Chicago, Chicago, United States.
Daniela Trejo-Ponce de LeonTechnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Mexico City, Mexico.
Gustavo Ramírez-MartínezLaboratory of Immunobiology and Genetics and Department of Pathology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.ORCID https://orcid.org/0000-0001-5157-0677
Luis Jiménez-AlvarezLaboratory of Immunobiology and Genetics and Department of Pathology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.ORCID https://orcid.org/0000-0002-5326-2720
Cesar Luna-RiveroLaboratory of Immunobiology and Genetics and Department of Pathology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.
Joaquin ZunigaTechnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Mexico City, Mexico.ORCID https://orcid.org/0000-0002-7143-0281
Deepak KaushalSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, United States.
Shabaana A KhaderDepartment of Microbiology, The University of Chicago, Chicago, United States.ORCID https://orcid.org/0000-0002-9545-4982

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
ROLE OF INDUCIBLE BRONCHUS ASSOCIATED LYMPHOID TISSUE IN LATENT TUBERCULOSISR01AI111914 · NIAID · WASHINGTON UNIVERSITY · PI KAUSHAL, DEEPAK, KHADER, SHABAANA A. · 2015 to 2025
$11.1M
ROLE OF IL-17 IN PROTECTIVE VACCINE-INDUCED IMMUNE RESPONSES AGAINST TUBERCULOSISR01HL105427 · NHLBI · WASHINGTON UNIVERSITY · PI KHADER, SHABAANA A. · 2011 to 2025
$5.9M
The Role of Group 3 Innate Lymphoid cells (ILC3) in TuberculosisR01AI134236 · NIAID · WASHINGTON UNIVERSITY · PI COLONNA, MARCO, KHADER, SHABAANA A. · 2017 to 2021
$4.4M
COMMON IMMUNE CORRELATES OF RISK OF TB DISEASE IN ANIMAL MODELS AND HUMANSR01AI123780 · NIAID · WASHINGTON UNIVERSITY · PI KAUSHAL, DEEPAK, KHADER, SHABAANA A. · 2016 to 2019
$2.9M
NHLBI NIH HHS R01 HL105427NIAID NIH HHS R01 AI111914NIAID NIH HHS R01 AI123780NIAID NIH HHS R01 AI134236NIH HHS AI111914NIH HHS AI123780NIH HHS AI134236NIH HHS HL105427NIH HHS P51 OD011133
6 · The paper itself

Abstract

Tuberculosis (TB), caused by the bacterium

Indexed as

Mast CellsMycobacterium tuberculosisTuberculosis, PulmonaryAnimalsChymasesDisease Models, AnimalDisease SusceptibilityHumansLungMiceChymaseschymasehumaninfectious diseasemast cellsmicrobiologymouseMycobacterium tuberculosisnon-human primatessusceptibility

Identifiers

PMID41603352
PMCPMC12851577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.