ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Sugar-Armored Pesticides: Self-Assembled System for Enhanced Foliar Adhesion and Sustained Delivery of Hydrophobic Antimicrobials Against Bacterial Diseases.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Naturally hydrophobic characteristics of most pesticides seriously affect their effective deposition and bioavailability on susceptible plants, causing inevitable off-target movement and environmental pollution. To solve this problem, we employ supramolecular self-assembly strategies to deliver and remedy such defective pesticides, thereby creating a self-assembled, multifunctional delivery system-PyE28@HP-β-CD, which comprises a high-performance pyridyl ether microbicide (PyE28) complexed with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD). This approach transforms insoluble hexagonal sheet structures (PyE28) into biocompatible sugar-armored spherical assemblies (PyE28@HP-β-CD) with sustained release profiles in aqueous environment, ultimately improving the physicochemical/biological properties and targeted delivery efficiency of hydrophobic pesticides. The advancement concretely manifests as: (i) markedly enhanced foliar deposition via improved wetting coverage and reduced interfacial tension (contact angle decreased by 18°), (ii) effective biofilm disruption (achieving an 81.40% biofilm reduction at 23.3 µg mL
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