Evidence map›Paper›PMID 41603037›Full record

ArticleCirculation2026

Breast Cancer Reveals Latent

Victoria Toro, Manon Mougin, Coline Brossat, Clement Jambon-Barbara, Alex Hlavaty, Charles Antoine Guay, Reem El Kabbout, Coralie Bilodeau, Yann Grobs, Sandra Martineau and 10 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Victoria Toro *Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).
Manon Mougin *Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).ORCID 0009-0005-2821-7345
Coline BrossatUniversité Grenoble Alpes, INSERM U1300, HP2, and INSERM CIC1406, Grenoble, France (C. Brossat, CJ.-B., A.H.).ORCID 0009-0000-6333-5674
Clement Jambon-BarbaraUniversité Grenoble Alpes, INSERM U1300, HP2, and INSERM CIC1406, Grenoble, France (C. Brossat, CJ.-B., A.H.).ORCID 0000-0002-6619-4130
Alex HlavatyUniversité Grenoble Alpes, INSERM U1300, HP2, and INSERM CIC1406, Grenoble, France (C. Brossat, CJ.-B., A.H.).ORCID 0009-0002-8483-5023
Charles Antoine GuayCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).
Reem El KabboutCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).
Coralie BilodeauCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).
Yann GrobsCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).ORCID 0000-0003-3200-3241
Sandra MartineauCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).ORCID 0009-0007-2596-3953
Sandra Breuils-BonnetCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).
Antonella Abi-SleimenCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).
Gregoire RuffenachInstitut National de la Santé et de la Recherche Médicale (INSERM) unité mixte de recherche (UMR)_S 999 Pulmonary Hypertension: Pathophysiology and Novel Therapies, Hôpital Marie Lannelongue, Le Plessis-Robinson, France (G.R., D.M., C.K.).
Olivier BoucheratCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).ORCID 0000-0002-5251-7488
Malik BisserierDepartment of Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY (M.B.).ORCID 0000-0001-8826-4649
Steeve ProvencherCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).ORCID 0000-0001-7535-9972
Sebastien BonnetCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).ORCID 0000-0001-5753-1900
David MontaniInstitut National de la Santé et de la Recherche Médicale (INSERM) unité mixte de recherche (UMR)_S 999 Pulmonary Hypertension: Pathophysiology and Novel Therapies, Hôpital Marie Lannelongue, Le Plessis-Robinson, France (G.R., D.M., C.K.).ORCID 0000-0002-9358-6922
Charles KhouriInstitut National de la Santé et de la Recherche Médicale (INSERM) unité mixte de recherche (UMR)_S 999 Pulmonary Hypertension: Pathophysiology and Novel Therapies, Hôpital Marie Lannelongue, Le Plessis-Robinson, France (G.R., D.M., C.K.).ORCID 0000-0002-8427-8573
François PotusCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada (V.T., M.M., C.A.G., R.E.K., C. Bilodeau, Y.G., S.M., S.B.-B., A.A.-S., O.B., S.P., S.B., F.P.).ORCID 0000-0003-1745-6445

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary arterial hypertension (PAH) and breast cancer disproportionately affect women.

methodsWe combined bioinformatic, epidemiologic, and experimental approaches. Public cancer datasets were mined for

results

conclusionsThese findings identify a reciprocal association between breast cancer and PAH mediated by defective

Indexed as

Bone Morphogenetic Protein Receptors, Type IIBreast NeoplasmsHypertension, PulmonaryAnimalsFemaleGenetic Predisposition to DiseaseHumansMyocytes, Smooth MuscleRatsSignal TransductionBMPR2 protein, humanBmpr2 protein, ratBone Morphogenetic Protein Receptors, Type IIanimal modelBMPR2breast cancerinflammationpulmonary hypertensiontumors

Identifiers

PMID41603037
PMCPMC12908636

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.