Evidence map›Paper›PMID 41602957›Full record

ArticleIranian journal of basic medical sciences2025

Najeeb Ullah Khan, Shamshad Ul Hassan, Bilal Aslam, Saqib Umer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of basic medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Therapeutic Potential ofFood science & nutrition · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Najeeb Ullah KhanInstitute of Physiology and Pharmacology, University of Agriculture, Faisalabad, Pakistan.
Shamshad Ul HassanInstitute of Physiology and Pharmacology, University of Agriculture, Faisalabad, Pakistan.
Bilal AslamInstitute of Physiology and Pharmacology, University of Agriculture, Faisalabad, Pakistan.
Saqib UmerDepartment of Theriogenology, University of Agriculture, Faisalabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To investigate the therapeutic potential of Materials and Methods: HPLC was performed to check the phytochemical composition of FCLE. Analysis of the drug-likeness of phytochemicals and molecular docking was conducted. Four groups of rats were allocated as negative control (NC), positive control (PC), standard (STD), and FCLE treatment groups. After the experiment, serum samples were collected to carry out biochemical analyses. Histopathological assessments of the heart and aorta tissues were performed. The heart tissue gene expression analysis was conducted. Results: Conclusion: Our results suggest that FCLE mitigates cardiac injury by modulating oxidative stress and apoptosis through dual oxidases, the Nrf2/Keap1 pathway, and related apoptotic signaling cascades.

Indexed as

Anti-oxidantsCardio protectionHigh-fat dietIsoproterenolMyocardial infarctionOxidative stressPhytomedicine

Identifiers

PMID41602957
PMCPMC12834012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.