ArticleFrontiers in surgery2025
Impact of prolonged postoperative antibiotic administration on postoperative complications in elderly patients undergoing colorectal cancer surgery.
Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
5 authors.
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Abstract
Propose: The purpose of this study was to investigate whether prolonged antibiotic usage beyond conventional practices could impact the incidence of postoperative complications in elderly patients undergoing colorectal cancer surgery. Materials and methods: Between January 2016 and December 2022, a total of 292 patients aged over 70 years who underwent curative resection for colorectal cancer were identified from a retrospective database. The study population was divided into two groups: the POD#1 group, consisting of patients who received postoperative antibiotics for 1 day ( Results: A significant difference between two groups was observed in the rates of total postoperative complications, infection-related complications and antibiotic reuse. In the POD#1 group, complications occurred at a rate of 25.7% ( Conclusion: In colorectal cancer patients over the age of 70, prolonged antibiotic usage demonstrated a reduction in the rate of postoperative complications, including anastomotic leakage. Considering the potentially fatal consequences of postoperative complications in the elderly, the advantages of extended antibiotic administration beyond conventional usage outweigh the concerns regarding complications or costs associated with antibiotics use.
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