Evidence map›Paper›PMID 41602921›Full record

ArticleFrontiers in surgery2025

Repeat posterior fossa exploration and external neurolysis for recurrent trigeminal neuralgia following microvascular decompression.

Zhong Liu, Jiao Xu, Ming-Liang Ren, Min-Hui Xu, Sha Chen, Xu-Zhi He, Xu-Hui Wang

Abstract read
In one paragraph

Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhong Liu *Department of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, China.
Jiao Xu *Department of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, China.
Ming-Liang RenDepartment of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, China.
Min-Hui XuDepartment of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, China.
Sha ChenKey Laboratory of Biochemistry and Molecular Pharmacology, Department of Pharmacology, Chongqing Medical University, Chongqing, China.
Xu-Zhi HeDepartment of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, China.
Xu-Hui WangDepartment of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Recurrence of trigeminal neuralgia (TN) after microvascular decompression (MVD) poses a challenge for neurosurgeons. This study aimed to investigate the effect of repeat posterior fossa exploration (RPFE) and external neurolysis for TN recurrence following MVD. Methods: Totally, 38 TN patients who experienced recurrence after MVD were included. All patients underwent RPFE and limited neurolysis. The Barrow Neurological Institute Pain Intensity Scale were utilized to evaluate preoperative pain and postoperative outcomes. Results: The median follow-up period was 63.8 months (range: 5-112 months). Thirty-three out of the 38 patients achieved excellent outcomes, 4 had good outcomes, and 1 experienced failure. The rates of complete pain relief was 92% immediately post-surgery and 86.8% at the final follow-up. Re-exploration revealed Teflon adhesion in almost all patients (92%). Complications included new facial numbness ( Conclusions: Teflon adhesion was frequently observed upon re-exploration. A substantial majority of TN patients experiencing recurrence post-MVD achieved positive outcomes via RPFE and neurolysis. Complications, particularly facial numbness attributed to premature excessive Teflon dislodgement, continue to pose challenges. However, limited neurolysis, have proven effective in minimizing these complications.

Indexed as

microvascular decompressionneurolysisrecurrenceTeflontrigeminal neuralgia

Identifiers

PMID41602921
PMCPMC12833354

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.