ArticleFrontiers in pediatrics2025
The exposure-outcome relationship between physical and psychosocial factors and non-specific back pain in adolescents: a systematic review and meta-analysis protocol.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Background: Non-specific back pain in adolescents is widely prevalent, with potential for chronicity in adulthood. Evidence points to various physical and psychosocial exposures of non-specific back pain in adolescents. Reviewing and synthesizing this evidence will help identify modifiable and non-modifiable exposures that can inform appropriate interventions. This systematic review and meta-analysis aims to estimate the global pooled prevalence of back pain in the age group of 10-19 years and describe the exposure-outcome relationships between various risk factors and non-specific back pain. We also aim to establish the dose-response relationship, if possible, between factors such as screen time exposure, BMI, psychological assessment scores, and non-specific back pain. Methods: A robust search strategy will be employed to search PubMed, PMC, and Scopus databases for articles in English. Observational studies that estimate the prevalence and severity of non-specific back pain in adolescents (age 10-19 years) will be included. Studies that have looked at exposures such as, but not limited to, the mode of transport to school, school bag weight, BMI, screen time exposure duration, physical activity, participants' perceptions, and psychological, familial, and social factors will be eligible. Two authors will independently screen articles for suitability using the Rayyan software, extract data using the Review Manager 5 software, and assess the risk of bias using the JBI tool for critical appraisal of observational studies. The global pooled prevalence will be calculated using the Freeman-Tukey transformed proportions in the common effect inverse variance model. In case of low heterogeneity ( Discussion: Identifying modifiable exposures of non-specific back pain can inform intervention strategies suitable for the individual or school setting. Systematic review registration: PROSPERO CRD42024572590.
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