Evidence map›Paper›PMID 41602860›Full record

ArticleFrontiers in reproductive health2025

An opportunity for fertility preservation in neurosurgical spinal ependymoma patients: a single center review.

Madison J Michles, Christian B Schroeder, Lauren R Sugarmann, Felicia W Sun, Morgan Kruzan, Luce Kassi, May-Tal Sauerbrun-Cutler, Ziya L Gokaslan, Patricia Zadnik Sullivan

Abstract read
In one paragraph

Article in Frontiers in reproductive health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Madison J MichlesDepartment of Neurosurgery, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, United States.
Christian B SchroederDepartment of Neurosurgery, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, United States.
Lauren R SugarmannDepartment of Neurosurgery, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, United States.
Felicia W SunDepartment of Neurosurgery, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, United States.
Morgan KruzanDepartment of Neurosurgery, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, United States.
Luce KassiDivision of Reproductive Endocrinology and Infertility, Women and Infants Hospital of Rhode Island, Providence, RI, United States.
May-Tal Sauerbrun-CutlerDivision of Reproductive Endocrinology and Infertility, Women and Infants Hospital of Rhode Island, Providence, RI, United States.
Ziya L GokaslanDepartment of Neurosurgery, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, United States.
Patricia Zadnik SullivanDepartment of Neurosurgery, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal ependymomas are intradural intramedullary tumors that present frequently in adults with a bimodal peak at 25-29 years and again at 45-59 years. The risk of progressive neurological deficit in these patients creates the need for surgical resection and radiation therapy. Myxopapillary ependymomas specifically occur at the conus medullaris within the lumbar spine, and these treatments can have a significant impact on patient fertility. However, recent reports illustrate that a vast majority of adults with cancer receive inadequate fertility preservation education, counseling, or resources, and providers tend to cite barriers such as lack of knowledge about fertility preservation options or referrals as well as discomfort with broaching the topic. This review aims to explore the extent to which fertility preservation counseling was offered by a neurosurgery department at a single institution to patients with ependymomas and the subsequent utilization of fertility preservation services. A retrospective review of our local spine tumor database from 2015 to 2025 identified 15 patients who underwent surgery for spinal ependymomas at Rhode Island Hospital. Patients who were outside of child-bearing years (<18 years to >44 years) were excluded (

Indexed as

fertility preservationneuro-oncologyneurosurgeryreproductive endocrinology and infertilityspinal ependymoma

Identifiers

PMID41602860
PMCPMC12832810

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.