Evidence map›Paper›PMID 41602783›Full record

ArticleO&G open2026

Validation Study of a Photo-Based Menstrual Blood Loss Metric.

Jacqueline Fahey, Ram K Parvataneni, L Elaine Waetjen, Jennifer C Fung, Vanessa L Jacoby

Abstract read
In one paragraph

Article in O&G open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jacqueline FaheyDepartment of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California; Department of Obstetrics and Gynecology, UC Davis School of Medicine, Sacramento, California; and Department of Obstetrics, Gynecology, and Reproductive Sciences, UC San Francisco School of Medicine, San Francisco, California.
Ram K ParvataneniDepartment of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California; Department of Obstetrics and Gynecology, UC Davis School of Medicine, Sacramento, California; and Department of Obstetrics, Gynecology, and Reproductive Sciences, UC San Francisco School of Medicine, San Francisco, California.
L Elaine WaetjenDepartment of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California; Department of Obstetrics and Gynecology, UC Davis School of Medicine, Sacramento, California; and Department of Obstetrics, Gynecology, and Reproductive Sciences, UC San Francisco School of Medicine, San Francisco, California.
Jennifer C FungDepartment of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California; Department of Obstetrics and Gynecology, UC Davis School of Medicine, Sacramento, California; and Department of Obstetrics, Gynecology, and Reproductive Sciences, UC San Francisco School of Medicine, San Francisco, California.
Vanessa L JacobyDepartment of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California; Department of Obstetrics and Gynecology, UC Davis School of Medicine, Sacramento, California; and Department of Obstetrics, Gynecology, and Reproductive Sciences, UC San Francisco School of Medicine, San Francisco, California.

Funding

A Photo-based Menstrual Blood Loss MetricR44HD102235 · NICHD · THERANOVA, LLC · PI BURNETT, DANIEL ROGERS, JACOBY, VANESSA · 2021 to 2023
$2.0M
NICHD NIH HHS R44 HD102235
6 · The paper itself

Abstract

objectiveTo validate an objective photo-based electronic method of quantifying menstrual blood loss against the current gold standard alkaline hematin method.

methodsIn this multicenter, prospective cohort study, 79 participants (33 in the training phase, 46 in the validation phase) 18-50 years of age who were premenopausal with self-reported heavy menstrual bleeding were recruited from February to November 2023. Participants provided demographic and medical history details at baseline and then used study-provided pads, photo mats, and smartphones to capture images of menstrual blood loss per pad in one menstrual cycle. A photo-based smartphone application used image analysis software to convert the surface area of blood staining on each menstrual pad into menstrual blood loss volume. The outcome measures were menstrual blood loss per pad and per cycle measured in milliliters, with the alkaline hematin method as the reference standard. Bland-Altman analysis was used with 46 participants from the validation phase to construct limits of agreement between the photo-based and alkaline hematin methods for measuring menstrual blood loss. The sensitivity and specificity of the photo-based method for diagnosing heavy menstrual bleeding (menstrual blood loss more than 80 mL per cycle) were also evaluated.

resultsThe photo-based method correlated strongly with the alkaline hematin reference standard for both per-pad (

conclusionA photo-based method provides a valid, practical, and accessible alternative to the alkaline hematin standard, enabling accurate diagnosis and monitoring of heavy menstrual bleeding in both clinical and research settings.

Identifiers

PMID41602783
PMCPMC12834436

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.