ArticleFrontiers in bioengineering and biotechnology2025
Exploring the differentiation potential of adipose tissue-derived mesenchymal stromal/stem cells and progenitor buccal epithelial cells into urothelial cells.
Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The intestinal wall is the most commonly used substitution material in reconstructive urology. However, this strategy is associated with many complications. Tissue engineering techniques can replace the intestinal wall with an Results: AD-MSCs subjected to urothelial differentiation changed their morphology from fibroblast-like to epithelium-like. In BECs, the differentiation factor increased the expression of urothelial markers, including Conclusion: This study demonstrated that pBECs have a higher potential to differentiate toward urothelial-like cells than AD-MSCs. UC-CM is the source of factors inducing the differentiation of pBECs toward urothelial-like cells. Buccal epithelium can be used as a cell source for reconstructive urology applications.
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