Evidence map›Paper›PMID 41602461›Full record

ArticleFrontiers in bioengineering and biotechnology2025

Biofunctional response of a synthetic ceramic of 99.9% tricalcium phosphate associated with a heterologous fibrin biopolymer and infrared photobiomodulation.

Carlos Henrique Bertoni Reis, Brenda Thaynne Lima de Matos, Cleuber Rodrigo de Souza Bueno, Benedito Barraviera, Rui Seabra Ferreira Júnior, Paulo Sérgio da Silva Santos, Marco Antonio Hungaro Duarte, Murilo Priori Alcalde, Dayane Maria Braz Nogueira, Geraldo Marco Rosa Júnior and 2 more

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carlos Henrique Bertoni ReisDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
Brenda Thaynne Lima de MatosDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
Cleuber Rodrigo de Souza BuenoDepartment of Anatomy, Medical and Dentistry School, University Center of Adamantina (FAI), Adamantina, Brazil.
Benedito BarravieraCenter for the Study of Venoms and Venomous Animals (CEVAP), São Paulo State University (Univ Estadual Paulista, UNESP), Botucatu, Brazil.
Rui Seabra Ferreira JúniorCenter for the Study of Venoms and Venomous Animals (CEVAP), São Paulo State University (Univ Estadual Paulista, UNESP), Botucatu, Brazil.
Paulo Sérgio da Silva SantosDepartment of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of São Paulo (USP), Bauru, Brazil.
Marco Antonio Hungaro DuarteDepartment of Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo (FOB/USP), Bauru, Brazil.
Murilo Priori AlcaldeDepartment of Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo (FOB/USP), Bauru, Brazil.
Dayane Maria Braz NogueiraPostgraduate Program in Applied Dental Sciences, Bauru School of Dentistry (FOB/USP), University of Sao Paulo, Bauru, Brazil.
Geraldo Marco Rosa JúniorDepartment of Anatomy, Medical and Dentistry School, University Center of Adamantina (FAI), Adamantina, Brazil.
Daniela Vieira BuchaimDepartment of Anatomy, Medical and Dentistry School, University Center of Adamantina (FAI), Adamantina, Brazil.
Rogério Leone BuchaimDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioproducts and biomaterials for repairing large bone defects hold significant promise in translational research, particularly within Medicine and Dentistry. This study investigated a novel biocomplex comprising a synthetic tricalcium phosphate biomaterial (B), a heterologous fibrin biopolymer formulation (F), and an intraoperative photobiomodulation (PBM) protocol to enhance critical-sized bone defect repair in rats. Sixty male Wistar rats were randomly allocated to six groups (

Indexed as

biocompatible materialsbone regenerationbone repairfibrin biopolymerfibrin gluefibrin sealantlow-level laser therapyphotobiomodulation

Identifiers

PMID41602461
PMCPMC12833300

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.