Evidence map›Paper›PMID 41602105›Full record

ArticleFrontiers in cellular and infection microbiology2025

Tricyclazole alleviates

Chunjiao Zheng, Wei Li, Yuanyuan Wang, Lulu Li, Linan Ni, Xiaoping Liu, Jingwen Tan, Lianjuan Yang, Qian Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chunjiao Zheng *Department of Medical Mycology, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Wei Li *Department of Medical Cosmetology, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Yuanyuan Wang *Department of Medical Mycology, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Lulu LiDepartment of Medical Mycology, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Linan NiDepartment of Medical Mycology, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Xiaoping LiuDepartment of Medical Mycology, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Jingwen TanDepartment of Medical Mycology, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Lianjuan YangDepartment of Medical Mycology, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Qian YuDepartment of Medical Mycology, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chromoblastomycosis (CBM) is a chronic cutaneous infection caused by dematiaceous fungi, characterized by therapeutic challenges such as difficulty in pathogen clearance and high recurrence rates. Objectives: This study aimed to investigate the effects of tricyclazole (TCZ) on Methods: We conducted Results: Conclusions: This study reveals a novel mechanism by which TCZ counteracts

Indexed as

Antifungal AgentsChromoblastomycosisFonsecaeaMelaninsNeutrophilsThiazolesAnimalsDisease Models, AnimalExtracellular TrapsFemaleHumansMiceNaphtholsOxidative StressReactive Oxygen Species1,8-dihydroxynaphthalene melaninAntifungal AgentsMelaninsNaphtholsReactive Oxygen SpeciesThiazolestricyclazolechromoblastomycosisDHN-melanin synthesisFonsecaea pedrosoiNETs (neutrophil extracellular traps)oxidative stresstricyclazole

Identifiers

PMID41602105
PMCPMC12832909

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.