Evidence map›Paper›PMID 41601806›Full record

ArticleFrontiers in medicine2025

Hybrid intelligent systems for liver disease prediction: a demographic-aware machine learning framework.

Ekta Saraf, Mao Yang, Ramalingam Sakthivel, Yiquan Zhang, Santosh Chokkakula, Yu Kong, Vykunta Alekya, Bommireddy Naveen, Bing Yang

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ekta Saraf *School of Computer Science and Engineering, Vellore Institute of Technology, Chennai, India.
Mao Yang *Department of Invasive Interventional Therapy, Tianjin Cancer Hospital, Airport Hospital, Tianjin, China.
Ramalingam Sakthivel *School of Computer Science and Engineering, Vellore Institute of Technology, Chennai, India.
Yiquan ZhangSchool of Pharmacy, Tianjin Medical University, Tianjin, China.
Santosh ChokkakulaDepartment of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.
Yu KongDepartment of Cell Biology, College of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Vykunta AlekyaSVU Health Centre, Sri Venkateswara University, Tirupati, Andhra Pradesh, India.
Bommireddy NaveenDepartment of Chemical and Biological Engineering, Gachon University, Seongnam, Gyeonggi, Republic of Korea.
Bing YangDepartment of Cell Biology, College of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Liver disease remains a major global health burden, often progressing undetected until advanced stages. Traditional diagnostic approaches, while accurate, are invasive, costly, and limited in accessibility. Objective: To address these challenges, we propose a hybrid intelligent framework that integrates demographic segmentation with advanced machine learning for the early detection of liver disease. Results: Two datasets were employed, including the Indian Liver Patient Dataset (ILPD, Conclusion: By combining demographic awareness, hybrid learning, and interpretability, this study offers a scalable, non-invasive, and clinically relevant tool for early detection of liver diseases, advancing personalized and accessible healthcare.

Indexed as

gender-age dynamic machine learninghybrid intelligentliver disease predictionmachine learning based classificationrandom forest

Identifiers

PMID41601806
PMCPMC12833304

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.