ArticleFrontiers in medicine2025
Comparison of inflammatory markers and microflora in cirrhotic patients with portal vein thrombosis: a retrospective study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This study investigates inflammatory markers and blood microflora in cirrhotic patients with portal vein thrombosis (PVT). Aims: This study explores inflammatory markers and microflora in cirrhotic patients with PVT. Methods: This retrospective study at Hebei General Hospital between September 2021 and December 2023 categorized patients into PVT and non-PVT groups. Portal and peripheral vein blood samples were collected during TIPS procedure, with inflammatory markers LPS, IL-6, IL-8, TNFα and sNox2-dp tested via ELISA and 16SrRNA sequencing of blood microflora. Results: The study included 28 cirrhotic patients: 12 in PVT group (5 males, mean age: 55.8 ± 11.2) and 16 in non-PVT group (13 males, mean age: 54.3 ± 13.6). Groups showed no differences in age, gender, or BMI( Conclusion: Pseudomonas and Microbacteriaceae were enriched in PVT portal blood. Rolstonia, Clostridium, Phenylobacterium, and Streptococcus correlated with LPS and IL-6 (
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