ArticleFrontiers in medicine2025
Preoperative prediction of lymph node metastasis in pancreatic ductal adenocarcinoma using MRI-derived whole-tumor ADC histogram analysis.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To evaluate the predictive value of whole-tumor apparent diffusion coefficient (ADC) histogram parameters derived from MRI for assessing lymph node metastasis (LNM) in pancreatic ductal adenocarcinoma (PDAC). Materials and methods: Preoperative MRI and clinical data from 53 patients with pathologically confirmed PDAC were retrospectively analyzed. Patients were divided into two groups: LNM ( Results: All ADC histogram parameters except the coefficient of variation and kurtosis showed significant differences between LNM and NLNM groups ( Conclusion: Whole-tumor ADC histogram analysis provides a non-invasive and quantitative tool for preoperative prediction of lymph node metastasis in PDAC. The integrated multiparametric model demonstrates superior diagnostic performance compared with single-parameter analysis.
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