Evidence map›Paper›PMID 41601736›Full record

ArticleFrontiers in medicine2025

Mortality risk factors in patients with bloodstream infections due to multidrug-resistant Gram-negative bacilli.

Ana Luisa Corona-Nakamura, Martha Judith Arias-Merino, Sussan Alely Urbina-Rosas, Martha Elena Vázquez-Arias, Juan Fernando Corona-Macías, Eduardo González-Espinoza, Jorge Andrade-Sierra, Arnulfo Hernán Nava-Zavala, Luis Humberto Govea-Camacho

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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana Luisa Corona-NakamuraDivision of Medicine, National Western Medical Center, Mexican Social Security Institute (IMSS), Guadalajara, Jalisco, Mexico.
Martha Judith Arias-MerinoWestern Clinical Research Center, Zapopan, Jalisco, Mexico.
Sussan Alely Urbina-RosasDivision of Medicine, National Western Medical Center, Mexican Social Security Institute (IMSS), Guadalajara, Jalisco, Mexico.
Martha Elena Vázquez-AriasHealth Sciences University Center, University of Guadalajara, Guadalajara, Jalisco, Mexico.
Juan Fernando Corona-MacíasHealth Sciences University Center, University of Guadalajara, Guadalajara, Jalisco, Mexico.
Eduardo González-EspinozaDivisions of Nephrology and Transplantation, National Western Medical Center, Mexican Social Security Institute (IMSS), Guadalajara, Jalisco, Mexico.
Jorge Andrade-SierraDivisions of Nephrology and Transplantation, National Western Medical Center, Mexican Social Security Institute (IMSS), Guadalajara, Jalisco, Mexico.
Arnulfo Hernán Nava-ZavalaSchool of Medicine International Program, Autonomous University of Guadalajara, Zapopan, Jalisco, Mexico.
Luis Humberto Govea-CamachoDepartment of Physiology, University Center for Health Sciences, University of Guadalajara, Guadalajara, Jalisco, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study aimed to analyze risk factors for mortality in hospitalized patients with bloodstream infections caused by multidrug-resistant Gram-negative bacilli in a retrospective cohort (January-December 2022). Methods: Hospitalized patients with positive monomicrobial blood cultures for GNB (from central venous catheters and peripheral venipuncture) were included. Medical records and blood culture isolates were reviewed. The primary endpoint was all-cause mortality at ≤ 30 days. Risk factor analysis was performed using univariate models, survival curves (Cox regression), and an adjusted Cox proportional hazards model. Results: A total of 126 patients with Gram-negative bacillus bloodstream infection were included, 36 of them died within ≤ 30 days, representing a mortality rate of 28.6%. Of these deaths, 32/36 (88.9%) were due to carbapenem-resistant bacilli. The most frequently isolated gram-negative bacilli were: Discussion: Having received ineffective empirical treatment was an independent predictor of mortality, with a hazard ratio (HR) of 10.2 (95% CI: 2.6-39.9;

Indexed as

bloodstream infectionscarbapenem-resistant Acinetobacter baumanniiineffective empirical treatmentmortalitymultidrug-resistant Gram-negative bacilli

Identifiers

PMID41601736
PMCPMC12833034

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.