ArticleFrontiers in child and adolescent psychiatry2025
Investigating the ADOS-2 calibrated severity score: insights from the ELENA cohort.
Article in Frontiers in child and adolescent psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02625116 (ELENA Cohort), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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ELENA Cohort: A Long-term Longitudinal Study in a Pediatric Sample With Autism Spectrum Disorders
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2 authors.
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Abstract
Introduction: The Autism Diagnostic Observation Schedule (ADOS-2) is widely used to assess Autism Spectrum Disorder (ASD) symptom severity. To allow comparisons across modules and developmental levels, the Calibrated Severity Score (ADOS-CSS) was developed. However, concerns have been raised about potential changes in the measurement signal introduced by the calibration process, which may alter the signal captured by the ADOS-2 raw scores (ADOS-RS). Methods: Using longitudinal data from the ELENA cohort ( Results: Variance explained by module, age, and IQ was higher for the ADOS-RS (R Discussion: While the ADOS-CSS facilitates standardized comparisons across modules, clinicians and researchers should be aware of potential distortions in the measurement signal associated with the calibration process. Clinical Trial Registration: NCT02625116.
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