ArticleFrontiers in immunology2025
Ferroptosis and immunity: a bibliometric analysis of research hotspots and frontiers (2012-2025).
Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- MicroRNA regulation in pulmonary fibrosis: a bibliometric analysis of global research trends, collaborative networks, and emerging frontiers.Frontiers in medicine · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Ferroptosis is a form of programmed cell death triggered by iron-dependent lipid peroxidation. Accumulating evidence has revealed potential associations between cellular Ferroptosis and infection, inflammation, and immunity. Given the substantial literature in this field, the present study aims to comprehensively overview the research hotspots and knowledge structure underlying the interplay between Ferroptosis and immunity via bibliometric analysis. Methods: Relevant literature focusing on Ferroptosis and immunity-published between January 1, 2012, and August 31, 2025-was retrieved from the Web of Science, PubMed, and Scopus databases. Bibliometric analyses, encompassing evaluations of national contributions, institutional collaborative networks, journal outputs, and keyword co-occurrence, were conducted using CiteSpace, VOSviewer, and Origin software. These analyses aimed to delineate research trends and project future research trajectories. Results: A total of 3,436 publications relevant to Ferroptosis and immunity were included in this study. The analysis revealed a continuous and steady growth in the number of articles published in this field over the past 12 years. At the national level, China leads in both publication output (H-index = 99) and institutional contributions, with Central South University and Sun Yat-sen University each accounting for 154 papers. In contrast, the United States (average citations per paper: 114.11) and Germany (average citations per paper: 142.92) demonstrate outstanding performance in research impact. Frontiers in Immunology stands out as the most prolific journal, with 162 published articles in this field. Keyword co-occurrence analysis indicated that the application of Ferroptosis in cancer immunotherapy currently constitutes the most prominent research focus. Conclusion: This study represents the first systematic bibliometric analysis of literature on Ferroptosis and immunity, leveraging data from the Web of Science, PubMed, and Scopus databases. These findings underscore that oncology and immunology are the dominant disciplines in this field, with Ferroptosis-targeted cancer immunotherapies and the modulation of the tumor immune microenvironment (TME) emerging as key frontiers. Strengthening international collaboration and focusing on high-impact research will facilitate the clinical translation of therapeutic strategies for immunity-related diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.