Evidence map›Paper›PMID 41601588›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2025

DARC and Anti-Duffy Antibodies in the Line of Fire: The Challenges in Pinpointing the Etiology of Microcirculation Inflammation to a Distinct Entity.

Farsad Eskandary, Günther F Körmöczi, Marlies Schönbacher, Gottfried Fischer, Ingrid Faé, Sabine Wenda, Daniela Koren, Rainer Oberbauer, Roman Reindl-Schwaighofer, Andreas Heinzel and 8 more

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In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Farsad EskandaryDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Günther F KörmöcziDepartment of Blood Group Serology and Cell Therapy, Medical University of Vienna, Vienna, Austria.
Marlies SchönbacherDepartment of Blood Group Serology and Cell Therapy, Medical University of Vienna, Vienna, Austria.
Gottfried FischerDepartment of Blood Group Serology and Cell Therapy, Medical University of Vienna, Vienna, Austria.
Ingrid FaéDepartment of Blood Group Serology and Cell Therapy, Medical University of Vienna, Vienna, Austria.
Sabine WendaDepartment of Blood Group Serology and Cell Therapy, Medical University of Vienna, Vienna, Austria.
Daniela KorenDepartment of Blood Group Serology and Cell Therapy, Medical University of Vienna, Vienna, Austria.
Rainer OberbauerDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Roman Reindl-SchwaighoferDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Andreas HeinzelDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Johannes KlägerDepartment of Pathology, Medical University of Vienna, Vienna, Austria.
Nicolas KozakowskiDepartment of Pathology, Medical University of Vienna, Vienna, Austria.
Stephan SegererDivision of Nephrology, Dialysis and Transplantation, Kantonsspital Aarau, Aarau, Switzerland.
Konstantin DobererDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Luis G HidalgoHistocompatibility and Immunogenetics Laboratory, University of Alabama at Birmingham, Birmingham, AL, United States.
Helga SchachnerDepartment of Pathology, Medical University of Vienna, Vienna, Austria.
Georg A BöhmigDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Heinz RegeleDepartment of Pathology, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody-mediated rejection (ABMR) due to non-HLA alloantibodies has gained substantial attention in transplantation research. One candidate for such non-HLA reactivity is the Duffy blood group carrier molecule DARC, which is not only expressed on erythrocytes, but also on kidney microvascular endothelial cells and is postulated as a potential transplantation-relevant alloantigen. However,

Indexed as

Duffy Blood-Group SystemInflammationIsoantibodiesKidney TransplantationReceptors, Cell SurfaceCapillariesComplement C4bFemaleGraft RejectionHumansKidneyMaleMicrocirculationPeptide FragmentsRetrospective StudiesACKR1 protein, humanComplement C4bcomplement C4dDuffy Blood-Group SystemIsoantibodiesPeptide FragmentsReceptors, Cell Surfaceantibody-mediated rejection (AMR)donor specific antibodiesDSADuffy blood grouphumoral rejection

Identifiers

PMID41601588
PMCPMC12832551

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.