ArticleRespirology case reports2026
A Case of IgG4-Related Disease That Mimics an Anterior Mediastinal Malignant Tumour.
Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- A Case of IgG4-Related Disease That Mimics an Anterior Mediastinal Malignant Tumour.Respirology case reports · 2026Article
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13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
IgG4-related disease (IgG4-RD) is a fibroinflammatory disease characterised by elevated serum IgG4 levels and marked infiltration of IgG4-positive plasma cells. Here, we present the case of a 49-year-old man who presented with dysphagia and hoarseness caused by an anterior mediastinal mass. As the fluorodeoxyglucose positron emission tomography (FDG-PET) SUVmax was 6.68 (early and delayed), malignancy was initially suspected. Serum IgG4 levels were slightly elevated at 148 mg/dL. Surgical biopsy revealed dense lymphoplasmacytic infiltration with storiform fibrosis and numerous IgG4-positive plasma cells, fulfilling the diagnostic criteria for IgG4-RD. Treatment with high-dose prednisolone (60 mg/day) rapidly resolved symptoms and markedly reduced the mass within 6 months. This case highlights the importance of considering IgG4-RD in the differential diagnosis of mediastinal tumours, even when FDG-PET shows abnormal accumulation and serum IgG4 levels are not particularly high.
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