Evidence map›Paper›PMID 41601486›Full record

ArticleFrontiers in psychiatry2025

Association of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and atherogenic index of plasma with obstructive sleep apnea.

Guilian Li, Mingzhu Deng, Guohua He, Yan Jiang, Zhen Wang, Cai Zhou, Wei Xu, Tieqiao Feng, Wengao Zeng, Jian Peng and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Guilian Li *Department of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Mingzhu Deng *Department of Neurology, The Second People's Hospital of Hunan Province (Brain Hospital of Hunan Province), Changsha, Hunan, China.
Guohua He *Department of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Yan Jiang *Department of Neurology, The Second People's Hospital of Hunan Province (Brain Hospital of Hunan Province), Changsha, Hunan, China.
Zhen WangDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Cai ZhouDepartment of Rehabilitation, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Wei XuDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Tieqiao FengDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Wengao ZengDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Jian PengDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Ling XiaoDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Dandan YangDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Kangping SongDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Fangyi LiDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obstructive sleep apnea (OSA) is a prevalent sleep disorder associated with metabolic, cardiovascular disorders. The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and atherogenic index of plasma (AIP) are thought to be better ways to detect cardiovascular diseases than single lipid parameters. The relationship between NHHR or AIP and OSA remains ambiguous. Methods: 454 consecutive patients with suspected OSA were enrolled between June 2023 and February 2025. The OSA was defined as the occurrence of more than 5 apnea-hypopnea index (AHI) events/h. Spearman's rank correlation analysis among the NHHR, AIP, AHI, and lowest SpO Results: Among the 454 recruited patients, 318 (70.04%) were diagnosed with OSA. A binary logistic regression model showed that the NHHR (odds ratio [OR], 1.559; 95% CI 1.268-1.915, Conclusions: Our study indicates the NHHR and AIP were independent risk factors for OSA and can be used as potential tools for OSA.

Indexed as

apnea-hypopnea indexatherogenic index of plasmalipid abnormalitynon-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratioobstructive sleep apnea

Identifiers

PMID41601486
PMCPMC12833340

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.